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Resolution of Lipemia Retinalis With Lifestyle Modification.
J Vitreoretin Dis
August 2024
Department of Ophthalmology & Visual Neurosciences, Minneapolis, MN, USA.
To describe a case of lipemia retinalis, a rare ocular manifestation of hypertriglyceridemia that is characterized by a creamy-white to salmon-colored appearance to the fundus. A 55-year-old man was referred for an evaluation for diabetic retinopathy and was subsequently found to have marked lipemia retinalis. The patient's triglyceride levels were 3141 mg/dL; therefore, treatment was initiated with high-intensity statin therapy and lifestyle modifications.
View Article and Find Full Text PDFThe Weight on Sight: Exploring the Links Between Obesity and Ocular Diseases.
Cureus
October 2024
Gastroenterology, Nevill Hall Hospital, Abergavenny, GBR.
Obesity is a significant public health concern with escalating levels worldwide creating a variety of socioeconomic challenges and imposing a serious risk factor for a range of complications which include diabetes, hypertension, cardiovascular disease, and stroke, all of which are primary causes of early death. Furthermore, there is growing evidence connecting obesity to the development of several ocular disorders. Excessive weight is a common denominator in the aetiology of many ocular pathologies such as diabetic retinopathy, idiopathic intracranial hypertension, cataract, high intraocular pressures, age-related macular degeneration, and retinal vascular diseases through the association with diabetes, hypertension, and dyslipidemia.
View Article and Find Full Text PDFLipemia retinalis following FLAG-Ida protocol in an 11-year-old patient with acute myeloid leukemia.
Eur J Ophthalmol
January 2025
Department of Pediatric Hematology and Oncology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Introduction: We report a case of early-onset lipemia retinalis secondary to the FLAG-Ida protocol in the treatment of acute myeloid leukemia (AML) in an 11-year-old girl.
Case Report: An 11-year-old patient, diagnosed with AML at four months old, experienced a relapse and was treated with the FLAG-Ida protocol (fludarabine, idarubicin, granulocyte-colony stimulating factor, and high-dose cytarabine). Prior to allogeneic stem cell transplantation, she underwent a pre-transplantation eye examination.
Diagnosis and stabilisation of familial chylomicronemia syndrome in two infants presenting with hypertriglyceridemia-induced acute pancreatitis.
JIMD Rep
July 2024
Department of Metabolic Medicine, The Royal Children's Hospital Melbourne Australia.
Familial chylomicronemia syndrome (FCS) is a rare disorder of triglyceride (TG) metabolism caused by loss of function variants in one of five known canonical genes involved in chylomicron lipolysis and clearance-, , , , and . Pathogenic variants in , which encodes the hydrolytic enzyme lipoprotein lipase, account for over 80%-90% of cases. FCS may present in infancy with hypertriglyceridemia-induced acute pancreatitis and is challenging to manage both acutely and in the long-term.
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