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Hypothesis: The porosity affects the rheological response of porous particle suspensions.

Experiments: Non-Brownian suspensions of porous particles immersed in a Newtonian Polyisobutene are investigated. Three different particles, with different porosity, pore structure and similar size, and non-porous irregular particles are used.

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Plants play a key role in the ecological restoration of urban wetlands. Previous studies have shown that heavy-metal accumulation capacities and adaptation strategies of wetland plants may be related to their life forms. In this study, pot experiments were conducted to investigate the effects of nitrogen (N) on the adaptation strategies of two evergreen and deciduous aquatic iris life forms under cadmium (Cd) stress.

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Tetramethylpyrazine attenuates the cancer stem cell like-properties and doxorubicin resistance by targeting HMGCR in breast cancer.

Phytomedicine

December 2024

Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, PR China; Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, PR China; Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing 210023, PR China. Electronic address:

Background: Tetramethylpyrazine (TMP), a key bioactive constituent derived from Ligusticum wallichii Franchat, has demonstrated efficacy in mitigating multidrug resistance (MDR) in human breast cancer (BC) cells. However, the precise mechanisms underlying its action remain poorly understood.

Purpose: Cancer stem cells (CSCs) are widely recognized as the primary contributors to MDR.

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Real-Time Observation of Clickable Cyanotoxin Synthesis in Bloom-Forming Cyanobacteria and .

Toxins (Basel)

December 2024

Research Department for Limnology, University of Innsbruck, Mondseestrasse 9, 5310 Mondsee, Austria.

Recently, the use of click chemistry for localization of chemically modified cyanopeptides has been introduced, i.e., taking advantage of promiscuous adenylation (A) domains in non-ribosomal peptide synthesis (NRPS), allowing for the incorporation of clickable non-natural amino acids (non-AAs) into their peptide products.

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Straw incorporation can improve soil fertility and soil structure. While numerous studies have explored the immediate impacts of straw return on soil properties and crop production, the legacy effects of long-term straw return remain less understood. In this study, the straw returning soil of a continuous 15 years (SS) and non-straw returning soil (NS) were collected from Dahe Experimental Station of Hebei Academy of Agriculture and Forestry Sciences in China.

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