Objectives: Our study aims to investigate the safety and efficiency of the Codonics Safe Label System (SLS) in a prospective simulation study.
Methods: Three sets of simulated experiments involving 82 anesthetists were carried out on patient simulator mannequins. The primary outcome assessed through the simulated experiments was the effectiveness of the SLS in avoiding vial swap errors. Secondary outcomes analyzed included the efficacy of the SLS in preventing syringe swap and the difference in time taken to prepare standardized drugs as compared with conventional methods.
Results: The SLS was associated with a significant reduction in all 4 stages of vial swap error. The incidence of wrong ampoule breakage was significantly lower in the SLS group compared with the conventional group (12.1% versus 38.5%, P = 0.007). The number of staff who drew the wrong ampoule was similarly lower in the SLS group compared with the conventional group (4.9% versus 33.3%, P = 0.001). The proportions of staff who eventually wrongly labeled the loaded syringe were 0% in the SLS group and 17.9% in the conventional group (P = 0.005).Drug preparation time was longer for the SLS group than for the conventional group (239.6 ± 45.9 versus 160.3 ± 46.5 seconds, P < 0.001).There was no significant difference in the incidence of syringe swap with the use of the SLS.
Conclusions: The use of the SLS is effective in reducing vial swap error, but not syringe swap errors, and is associated with increased time taken for anesthetic drug preparation.
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http://dx.doi.org/10.1097/PTS.0000000000000875 | DOI Listing |
J Environ Manage
January 2025
College of Geographic Science and Tourism, Xinjiang Normal University, Urumqi, 830017, China. Electronic address:
The changes in lake ice phenology (LIP) can intuitively reflect the climate evolution in the regions where lakes are located, serving as an important indicator of climate change. The Tianshan Mountains, situated at the southern edge of freezing lakes in the Northern Hemisphere, are a crucial water resource base in Xinjiang and support significant ecosystems closely related to human activities. In the context of intensified climate change, this study focuses on the geographical location, altitude, and water quality differences among large lake groups in the mid-latitude region of Xinjiang, aiming to explore the characteristics of LIP changes in these lakes and their responses to driving factors, thereby providing a basis for effective environmental management and protection.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Dermatology and Venereology, Ryhov County Hospital, Sjukhusgatan, 553 05 Jönköping, Sweden.
: Lichen Sclerosus (LSc) is a chronic inflammatory skin condition predominantly affecting the anogenital regions, with a well-recognised potential for malignancy. This study examines the incidence, demographic characteristics, and regional distribution of LSc in Sweden over a 20-year period. The analysis is based on data from the Swedish National Patient Register (NPR), with a focus on cases diagnosed in specialist care settings.
View Article and Find Full Text PDFLife Sci
December 2024
State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China. Electronic address:
Aims: This study aimed to explore the molecular pathological mechanisms of the liver in metabolic disease-susceptible transgenic pigs via multiomics analysis.
Materials And Methods: The triple-transgenic (PNPLA3-GIPR-hIAPP) pig model (TG pig) was successfully constructed in our laboratory via the CRISPR/Cas9 technique previously described. Wild-type (WT) pigs and TG pigs after 2 or 12 months of high-fat and high-sucrose diet (HFHSD) induction (WT2, TG2, WT12, and TG12 groups, respectively) were used as materials.
Biosci Biotechnol Biochem
December 2024
Laboratory of Plant Chemical Regulation, School of Agriculture, Meiji University. 1-1-1, Higashi-Mita, Tama-ku, Kawasaki, Kanagawa, Japan.
Strigolactones (SLs) are apocarotenoid plant hormones that regulate shoot branching. The natural SLs can be divided into two groups, canonical and non-canonical SLs according to those chemical structures. In a model plant, Arabidopsis thaliana, it has been thought to produce only non-canonical SLs.
View Article and Find Full Text PDFNeurology
January 2025
From the Department of Neurology (J.N.D., H.T.M.B., N.V.A., B.G.M.V.E., N.C.V.); Department of Pediatric Neurology (J.N.D., H.T.M.B., A.K., C.E.E.), Donders Institute for Brain, Cognition and Behaviour, Amalia Children's Hospital, Radboud University Medical Centre, Nijmegen, The Netherlands; Department of Neurology (R.J.M.G.), Jönköping, and Department of Biomedical and Clinical Sciences, Linköping University, Sweden; Department of Rehabilitation (M.M.P., S.L.S.H.), Donders Institute for Brain, Cognition and Behaviour, Amalia Children's Hospital; and Department of Neurology (N.V.A.), Clinical Neuromuscular Imaging Group, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
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