The coronavirus disease 2019 (COVID-19) pandemic has caused a major outbreak around the world with severe impact on health, human lives, and economy globally. One of the crucial steps in fighting COVID-19 is the ability to detect infected patients at early stages and put them under special care. Detecting COVID-19 from radiography images using computational medical imaging method is one of the fastest ways to diagnose the patients. However, early detection with significant results is a major challenge, given the limited available medical imaging data and conflicting performance metrics. Therefore, this work aims to develop a novel deep learning-based computationally efficient medical imaging framework for effective modeling and early diagnosis of COVID-19 from chest x-ray and computed tomography images. The proposed work presents "WEENet" by exploiting efficient convolutional neural network to extract high-level features, followed by classification mechanisms for COVID-19 diagnosis in medical image data. The performance of our method is evaluated on three benchmark medical chest x-ray and computed tomography image datasets using eight evaluation metrics including a novel strategy of cross-corpse evaluation as well as robustness evaluation, and the results are surpassing state-of-the-art methods. The outcome of this work can assist the epidemiologists and healthcare authorities in analyzing the infected medical chest x-ray and computed tomography images, management of the COVID-19 pandemic, bridging the early diagnosis, and treatment gap for Internet of Medical Things environments.
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http://dx.doi.org/10.3389/fonc.2021.811355 | DOI Listing |
Curr Med Imaging
January 2025
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong An Road, Xicheng District, Beijing 100050, China.
Background: The neuroanatomical basis of white matter fiber tracts in gait impairments in individuals suffering from Parkinson's Disease (PD) is unclear.
Methods: Twenty-four individuals living with PD and 29 Healthy Controls (HCs) were included. For each participant, two-shell High Angular Resolution Diffusion Imaging (HARDI) and high-resolution 3D structural images were acquired using the 3T MRI.
Comb Chem High Throughput Screen
January 2025
Shanghai Key Laboratory of Molecular Imaging, Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Objective: Colorectal Cancer (CRC) has attracted much attention due to its high mortality and morbidity. Cordycepin, also known as 3'-deoxyadenosine (3'-dA), exhibits many biological functions, including antibacterial, anti-inflammatory, antiviral, anti-tumor, and immunomodulatory effects. It has been proven to show anticancer activity in both laboratory research studies and living organisms.
View Article and Find Full Text PDFCurr Cancer Drug Targets
January 2025
Department of Clinical Laboratory, Gongli Hospital of Shanghai Pudong New Area, Shanghai, 200135, China.
Background: Lenvatinib is an oral tyrosine kinase inhibitor that selectively inhib-its receptors involved in tumor angiogenesis and tumor growth. It is an emerging first-line treatment agent for hepatocellular carcinoma (HCC). However, there is no intravenous ad-ministration of Lenvatinib.
View Article and Find Full Text PDFCurr Med Chem
January 2025
Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Mahesana, Gujarat, 384012, India.
Therapeutic hurdles persist in the fight against lung cancer, although it is a leading cause of cancer-related deaths worldwide. Results are still not up to par, even with the best efforts of conventional medicine, thus new avenues of investigation are required. Examining how immunotherapy, precision medicine, and AI are being used to manage lung cancer, this review shows how these tools can change the game for patients and increase their chances of survival.
View Article and Find Full Text PDFCirc Cardiovasc Qual Outcomes
January 2025
Department of Medicine, Cardiovascular Division, University of Virginia Health, Charlottesville, Virginia, USA. (P.F.R.L., C.C.S.).
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