Impact of Regions with COVID-19 Cases on COVID-Zero Regions by Population Mobility - Worldwide, 2021.

What Is Already Known About This Topic?: Reducing population mobility and increasing the vaccination rate for severe acute respiratory syndrome coronavirus 2 can decrease the transmission of coronavirus disease 2019 (COVID-19).

What Is Added By This Report?: In order to reduce the incidence of COVID-19 to the levels of influenza after restoring normal mobility, the efficacy against infection needs to be increased to 40% and the efficacy against symptomatic disease needs to be increased to 90%. The efficacy against infection has a more important impact compared to efficacy against symptomatic disease or death on the transmission of COVID-19 at the population level.

What Are The Implications For Public Health Practice?: The population should continue maintaining non-pharmaceutical interventions and minimize international movement to prevent transmission of COVID-19. Furthermore, developing new vaccines or promoting booster vaccinations should be considered to increase efficacy.