The effect of drum drying conditions on functional properties of a nutritious, gluten-free instant fermented (tarhana) soup which was developed for celiac people by a partial substitution of rice flour with mung bean flour (1:1, w/w) was investigated. Response surface method was used to optimize drum drying process conditions for development of mung bean fortified soup. Impacts of independent variables; feed moisture (45-55-65%), drum rotating speed (0.6-1.4-2.2 rpm) and steam pressure (75-85-95 psi) on water and oil absorption capacities, foam capacity, foam stability, protein solubility and flow behavior were investigated. Responses were significantly affected by process variables. Feed moisture was the main factor affecting water and oil absorption capacity and viscosity, while drum rotating speed primarily affected protein solubility, foam capacity and stability. Maximum foaming abilities were obtained at high drum speeds and low feed moistures. Optimum process conditions were determined as 62.22% feed moisture, 2.20 rpm rotating speed, 75 psi pressure, with a desirability value of 0.693. The best achievable response values predicted by numerical optimization for these combinations were water absorption capacity: 3.25 mL/g, oil absorption capacity: 0.51 mL/g, protein solubility: 2.68 mg/mL, foam capacity: 0.07 mL/mL, foam stability: 14.59 min, and consistency coefficient: 2.04. Gluten-free mung bean-rice soup with increased protein content (20.52-22.62%) and functional properties along with higher dietary fiber (2.63-3.94%) will contribute to life quality of celiac patients.
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http://dx.doi.org/10.1007/s13197-021-05105-5 | DOI Listing |
ACS Nano
November 2024
Cardiovascular Medical Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
Gene therapy has emerged as a promising approach to address challenging cardiovascular diseases. Extensive efforts have been focused on developing highly efficient gene vectors with precise delivery techniques to enhance its effectiveness. In this study, we present multifunctional dopamine-gelatin microneedle patches with gene therapy capabilities to achieve perivascular gene delivery for intimal hyperplasia treatment.
View Article and Find Full Text PDFIran J Basic Med Sci
January 2024
Department of Orthopedics, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu, China.
Objectives: Osteoporosis is a significant public health concern due to its association with fragility fractures. Despite experiencing such fractures, many patients remain at high risk of future fractures due to inadequate management and treatment of their underlying osteoporosis. This research presents a comprehensive intervention to enhance osteoporosis management in patients with fragility fractures.
View Article and Find Full Text PDFHeliyon
August 2024
Functional Food and Nutrition Program, Faculty of Agro-Industry, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand.
Elderly people are susceptible to malnutrition due to many factors. An essential public health priority is ensuring that seniors have appropriate nutrition to prevent and treat malnutrition and dehydration as well as fulfilling the nutrition necessity. This study was conducted to utilize selected legumes and mushrooms to develop a high-protein instant soup (HPIS) product that is nutritious and suitable for the consumption of the elderly.
View Article and Find Full Text PDFFood Sci Biotechnol
September 2024
Department of Food Technology, Faculty of Food Science and Technology, Universiti Putra Malaysia, UPM, 43400 Serdang, Selangor Malaysia.
Anthocyanins (ACNs) are water-soluble pigments in various fruits and vegetables known for their high antioxidant activity. They are used as natural food colorants and preservatives and have several medicinal benefits. However, their application in functional foods and nutraceuticals is often compromised by their low stability to heat, oxygen, enzymes, light, pH changes, and solubility issues.
View Article and Find Full Text PDFPharmaceutics
June 2024
AbbVie Deutschland GmbH & Co. KG, Knollstraße 50, 67061 Ludwigshafen, Germany.
The present study compared vacuum drum drying (VDD) and conventional spray drying (SD) for solidifying crystalline ABT-199 nanosuspensions into redispersible oral drug products. The aim was to optimize formulation compositions and process conditions to maintain nanoparticle size after tablet redispersion. The impact of drug load (22%, 33%, 44%) and type of drying protectant (mannitol, mannitol/trehalose mix (1:1), trehalose) on redispersibility and material powder properties were investigated.
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