AI Article Synopsis
- Fixed low dead space syringes (LDSS) retain less blood post-injection than detachable needle syringes, but their impact on reducing blood-borne virus transmission is not well-studied.
- A study using UK data from 2016 to 2019 involved 1,429 people who inject drugs (PWID) to investigate the association between syringe type and hepatitis C virus infection.
- Results showed that always using fixed LDSS was linked to a 76% lower likelihood of recent hepatitis C virus infection among antibody-negative PWID compared to those using detachable needle syringes.
Article Abstract
Syringes with attached needles (termed fixed low dead space syringes [LDSS]) retain less blood following injection than syringes with detachable needles, but evidence on them reducing blood-borne virus transmission among people who inject drugs (PWID) is lacking. Utilizing the UK Unlinked Anonymous Monitoring cross-sectional bio-behavioral surveys among PWID for 2016/18/19 (n = 1429), we showed that always using fixed LDSS was associated with 76% lower likelihood (adjusted odds ratio = 0.24, 95% confidence interval [CI]: .08-.67) of recent hepatitis C virus infection (RNA-positive and antibody-negative) among antibody-negative PWID compared to using any syringes with detachable needles.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522423 | PMC |
| http://dx.doi.org/10.1093/cid/ciac140 | DOI Listing |
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