The selection of Leishmania hybrids in axenic culture was considered rare until recently, when Louradour and Ferreira et al., demonstrated that induced DNA damage facilitates genetic exchange, resulting in full genome tetraploid progenies in vitro. Meiosis-related gene homologues HAP2, GEX1, and RAD51 were found to be involved, opening new avenues for functional genomic studies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pt.2022.02.001 | DOI Listing |
Publication Analysis
Top Keywords
sex pressure
4
pressure stress
4
stress facilitates
4
facilitates leishmania
4
leishmania vitro
4
vitro hybridization
4
hybridization selection
4
selection leishmania
4
leishmania hybrids
4
hybrids axenic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!