The purpose of this study was to develop prediction models based on an incremental treadmill test to volitional exhaustion utilizing the modified Heck protocol. A total of 598 professional and youth athletes participating in different sports were recruited for this study. Specifically, the study enrolled professional male soccer players (n=380), professional male futsal players (n=24), elite male basketball players (n=27), professional male soccer referees (n=50), elite female soccer players (n=19), youth male basketball players (13-14 yrs n=15, 15-17 yrs n=20) and youth male soccer players (15 yrs n=28, 16-17 yrs n=35). Anthropometric measurements included stature, body mass, and body fat. Furthermore, all participants performed incremental cardiopulmonary exercise testing on a treadmill using the modified Heck protocol. Through multiple regression analysis, a separate prediction model was developed for each of the athletic populations. Results demonstrated that a significant (p=0.001) proportion of the variation observed in VOmax was explained by the variation in running time. The generated VOmax regression equations would allow athletes and coaches to predict VOmax in a relatively short time without the need for expensive and sophisticated equipment. To our knowledge, this is the first study that provides regression models for different athletic populations using the modified Heck protocol.
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Sci Rep
January 2025
Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, 622 West 168th Street, Ste. 876, New York, NY, 10032, USA.
The COVID-19 pandemic may have exacerbated mental health conditions by introducing and/or modifying stressors, particularly in university populations. We examined longitudinal patterns, time-varying predictors, and contemporaneous correlates of moderate-severe psychological distress (MS-PD) among college students. During 2020-2021, participants completed self-administered questionnaires quarterly (T1 = 562, T2 = 334, T3 = 221, and T4 = 169).
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Department of Chemistry, Zhejiang University, Hangzhou, 310058, China.
Heck silylation of unactivated alkenes is an efficient strategy for the synthesis of useful organosilicon compounds. However, extensive efforts have been dedicated to only achieving achiral molecules. Herein, a highly regio- and enantioselective cobalt-catalyzed Heck silylation of unactivated alkenes with hydrosilanes is reported for the first time, providing access to axially chiral alkenes in good to excellent yields with 87-98 % ee.
View Article and Find Full Text PDFClin Kidney J
January 2025
Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Bone and Mineral Research Unit, REDinREN (RD06/0016/1013, RD12/0021/0023 and RD16/0009/0017) and RICORS2040 (RD21/0005/0019) del ISCIII, Oviedo, Spain.
Background: Ageing often affects biomarker production. Yet, clinical/optimal thresholds to guide clinical decisions do not consider this. Serum albumin decreases with age, but hypoalbuminaemia is defined as serum albumin <4.
View Article and Find Full Text PDFCell Rep
September 2024
Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands; BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:
Trained immunity is characterized by histone modifications and metabolic changes in innate immune cells following exposure to inflammatory signals, leading to heightened responsiveness to secondary stimuli. Although our understanding of the molecular regulation of trained immunity has increased, the role of adaptive immune cells herein remains largely unknown. Here, we show that T cells modulate trained immunity via cluster of differentiation 40-tissue necrosis factor receptor-associated factor 6 (CD40-TRAF6) signaling.
View Article and Find Full Text PDFRheumatol Int
October 2024
Department of Medicine II, Rheumatology/Clinical Immunology, University Hospital of Wuerzburg, Oberdürrbacher Straße 6, 97080, Wuerzburg, Germany.
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