Introduction: Contralateral axillary lymph node metastasis (CAM) is rare, especially in primary breast cancer.
Presentation Of Case: A 71-year-old woman visited our hospital after noticing a mass in her right breast. A mass of 5 cm in diameter with skin infiltration was palpable on the medial side of the right breast. She underwent a needle biopsy and was diagnosed with invasive ductal carcinoma. On various imaging modalities, there were no distant metastases but bilateral axillary lymph node metastases were found. She underwent preoperative chemotherapy and showed a clinical partial response. After thorough discussion, she opted for surgery and underwent partial mastectomy of the right breast and bilateral axillary lymph node dissection. Histopathological examination revealed residual breast tumor and one metastatic axillary lymph node on each side. Postoperative radiotherapy and hormone therapy were performed. The patient is alive and recurrence-free as of 1 year after the start of treatment.
Conclusion: CAM is often regarded as distant metastasis, but can be considered curable if there is no distant metastasis to other organs. CAM without distant metastasis to other organs should be treated with curative intent in order to avoid a disadvantage to the patient.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857439 | PMC |
http://dx.doi.org/10.1016/j.ijscr.2022.106810 | DOI Listing |
Eur Radiol
December 2024
Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532 SZ, Nijmegen, The Netherlands.
Objectives: Quality control in breast cancer screening programmes has been subject of several studies. However, less is known about the clinical diagnostic work-up in recalled women with a suspicious finding at screening mammography. The current study focuses on interhospital differences in diagnostic work-up strategies.
View Article and Find Full Text PDFBreast Cancer (Dove Med Press)
December 2024
Department of Radiology, People's Hospital of Henan University, Zhengzhou, Henan, People's Republic of China.
Background: Core biopsy sampling may not fully capture tumor heterogeneity. Radiomics provides a non-invasive method to assess tumor characteristics, including both the core and surrounding tissue, with the potential to improve the accuracy of HER-2 status prediction.
Objective: To explore the clinical value of intratumoral and peritumoral radiomics features from dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) for preoperative prediction of human epidermal growth factor receptor-2 (HER-2) expression status in breast cancer.
Med Phys
December 2024
The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas, USA.
Background: Automation in radiotherapy presents a promising solution to the increasing cancer burden and workforce shortages. However, existing automated methods for breast radiotherapy lack a comprehensive, end-to-end solution that meets varying standards of care.
Purpose: This study aims to develop a complete portfolio of automated radiotherapy treatment planning for intact breasts, tailored to individual patient factors, clinical approaches, and available resources.
Quant Imaging Med Surg
December 2024
Department of Radiology, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Background: The heterogeneity within breast cancer and its microenvironment are associated with metastasis. Analyzing distinct tumor subregions using habitat analysis and characterizing the tumor microenvironment through radiomics may be valuable for predicting axillary lymph node metastasis (ALNM) in breast cancer. This study aimed to develop and validate a nomogram for predicting ALNM in breast cancer patients by integrating clinicopathological, intra- or peri-tumoral radiomic, and habitat signatures based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and determine the optimal peritumoral region size for accurate prediction.
View Article and Find Full Text PDFCureus
November 2024
Department of Pathology, Father Muller Medical College, Mangalore, IND.
Axillary swellings, particularly in women, often raise suspicion due to the high association of such swellings with breast carcinoma manifesting as metastatic lymph node involvement. Tuberculous lymphadenopathy is one of the primary diagnoses in India. Fibroadenomas are common benign breast tumors, but their occurrence in the axilla, arising from ectopic breast tissue (EBT), is rare and may present a diagnostic challenge.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!