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WHO's 2013 PMTCT guidelines recommended lifelong antiretroviral therapy (ART) for HIV-infected pregnant and breastfeeding women, exclusive breastfeeding (EBF), nevirapine prophylaxis (NVP) and early infant diagnosis (EID) for HIV-exposed-breastfed infants. We examined the association between knowledge and adherence to these guidelines among 550 HIV-infected pregnant women in Maharashtra, India. Knowledge of PMTCT guidelines was assessed using a structured-questionnaire during enrollment.
View Article and Find Full Text PDFHigh dose aflibercept treatment in naive neovascular age-related macular degeneration.
Int Ophthalmol
January 2025
Beyoglu Eye Training and Research Hospital, University of Health Sciences, Bereketzade Camii Sk. No:2 Beyoğlu, 34421, Istanbul, Turkey.
Background: To evaluate the efficacy and safety of intravitreal injections of 4 mg (high dose) of aflibercept in treatment-naive patients with neovascular AMD(nAMD) with treat and extend(TREX) dosing regimens, and to determine the frequency of injections.
Methods: In this interventional, retrospective study a total of 15 eyes of 14 patients (eight female and 9 male) with nAMD were included. All patients were examined and OCT imaging was performed at the time of initial presentation, on the day of each injection and at subsequent follow-up visits.
Global Dynamic Impression for Differentiating Between Epileptic and Psychogenic Nonepileptic Seizures: A Feasibility Study.
Brain Behav
January 2025
Technion Faculty of Medicine, Haifa, Israel.
Objective: Medical personnel show difficulty in differentiating psychogenic nonepileptic seizures (PNES) from epileptic seizures (ES). The purpose of this study was to conduct an initial feasibility assessment of the global dynamic impression (GDI) principle and to evaluate its effectiveness in enabling the diagnosis of epileptic versus psychogenic seizures using video footage of events, even by untrained personnel METHODS: We based this study on video footage showing five videos of PNES and five ES videos. We asked physicians and nurses from the emergency department, internal medicine department, neurology department, and medical students to classify the videos before and after learning the GDI principle.
View Article and Find Full Text PDFPublic perceptions of meniscus tears: Evaluating knowledge gaps and the role of education.
J Clin Orthop Trauma
February 2025
Department of Orthopaedics, Vanderbilt University Medical Center, 1215 21st Avenue South, 4200 Medical Center East, Nashville, TN, 37232-8774, USA.
Background: Meniscus tears are common, occurring acutely during sports or as degenerative tears with aging. Limited information exists about the public's understanding of these injuries and their management.
Hypothesis/purpose: This study aimed to evaluate the public's baseline understanding of meniscus tear management and assess the effectiveness of an educational intervention to improve their understanding.
Optimizing Surgical Correction of Symblepharon Secondary to Lower Eyelid Burn Scar.
Cureus
December 2024
Plastic and Reconstructive Surgery, Hospital de Santa Maria, Unidade Local de Saúde de Santa Maria (ULSSM), Lisbon, PRT.
The healing of lower eyelid injuries can lead to anatomical distortion and compromise the function of multiple periocular structures. To restore eyelid function and aesthetics, it is crucial to establish an accurate diagnosis and provide appropriate treatment to the affected structures. The presented case describes the diagnosis and surgical treatment of a lower eyelid symblepharon, which can be easily misdiagnosed as other scarring sequelae.
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