Effects of increasing levels of orange peel extract on kit growth, feed utilization, and some blood metabolites in the doe rabbits under heat stress conditions.

One of the most severe consequences of climate change on the rabbit production sector is heat stress. Dietary supplementation of phytochemicals could alleviate the negative impact of heat stress on rabbits. Thirty-six V-line rabbit does with average live body weight (LBW) of 2.672 ± 0.031 kg were randomly allocated into three experimental groups as follows: the control group (OPE) and the OPE and OPE groups were orally administered orange peel extract (OPE) at doses of 2.5 and 5 mL/doe. The increasing OPE levels significantly improved LBW at partum ( = 0.002) and weaning ( = 0.004), daily and total feed intake from pregnancy until weaning ( = 0.007), daily milk yield per doe at 7th and 14th days ( ≤ 0.05), and milk efficiency ( = 0.001). Litter size at 1-28 days, litter weight gain, survival rate, and kit weight gain at 21-28 days of heat-stressed doe rabbits were significantly improved with OPE treatments. The treatment of OPE significantly decreased serum glucose, triglycerides, and very-low-density lipoprotein-cholesterol levels of rabbits. The increasing OPE levels decreased significantly total lipid and low-density lipoprotein-cholesterol levels and increased ( = 0.001) high-density lipoprotein-cholesterol concentration in heat-stressed rabbits. In conclusion, the treatment of OPE improved feed utilization, milk efficiency, and reproductive performance and alleviated the drastic impacts of heat stress on rabbits.