AI Article Synopsis
- This study examined how well deep tissue cultures from shoulder surgeries detect Cutibacterium, a common bacteria found during such procedures.
- Researchers sent blind samples to multiple institutions and found that cultures with higher concentrations of Cutibacterium consistently tested positive, while lower concentrations showed mixed results.
- Results indicated that true-positive cultures (indicative of real infection) showed a significantly shorter time to positive results and stronger positivity metrics compared to false-positive cultures, suggesting the need for careful interpretation in clinical settings.
Article Abstract
Background: Deep tissue culture specimens obtained at the time of revision shoulder arthroplasty are commonly positive for Cutibacterium. Clinical interpretation of positive cultures can be difficult. This was a multi-institutional study evaluating the accuracy of cultures for Cutibacterium using positive control (PC) and negative control (NC) samples. The relationship between time to culture positivity and strength of culture positivity was also studied.
Methods: Eleven different institutions were each sent 12 blinded samples (10 PC and 2 NC samples). The 10 PC samples included 2 sets of 5 different dilutions of a Cutibacterium isolate from a failed total shoulder arthroplasty with a probable periprosthetic infection. At each institution, the samples were handled as if they were received from the operating room. Specimen growth, time to culture positivity, and strength of culture positivity (based on semiquantitative assessment) were reported.
Results: A total of 110 PC samples and 22 NC samples were tested. One hundred percent of specimens at the 4 highest dilutions were positive for Cutibacterium. At the lowest dilution, 91% of samples showed positive findings. Cutibacterium grew in 14% of NC samples. Cutibacterium grew in PC samples at an average of 4.0 ± 1.3 days, and all of these samples showed growth within 7 days. The time to positivity was significantly shorter (P < .001) and the strength of positivity was significantly higher (P < .001) in true-positive cultures compared with false-positive cultures.
Conclusions: This multi-institutional study suggests that different institutions may report highly consistent rates of culture positivity for revision shoulder arthroplasty samples with higher bacterial loads. In contrast, with lower bacterial loads, the results are somewhat less consistent. Clinicians should consider using a shorter time to positivity and a higher strength of positivity as adjuncts in determining whether a tissue culture sample is a true positive.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jse.2022.01.127 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A systematic Review of Spirituality Tools Based on Psychometric Qualities and Recommendations for Future Research.
J Relig Health
December 2024
Department of Yoga and Spirituality, SVYASA University, Prashanti Kutiram, Vivekanand Road, Kallubalu Post Jigani, Anekal Taluk, Bangalore, 560105, India.
Spiritual lifestyles positively impact physical and mental health, which can be addressed by effective spiritual tools. This review systematically evaluates general spirituality instruments retrieved from various databases. Among the top four validated tools with strong psychometric properties, each exhibited a limitation-such as contamination, absence of subscales, or lack of confirmatory factor analysis-which impacts their broader applicability.
View Article and Find Full Text PDFSafety and Efficacy of Percutaneous Drain Placement for Postsurgical Breast Region Fluid Collections.
J Breast Imaging
December 2024
Department of Radiology, Stanford Medicine, Stanford, CA, USA.
Objective: The purpose of this study was to describe the safety and efficacy of percutaneous drain placement for postoperative fluid collections in the breast.
Methods: A retrospective review was conducted of the patient characteristics, intervention data, and clinical outcomes of the 43 adult patients who underwent percutaneous drain placement for fluid collections at a tertiary care hospital over a 13-year period ending February 28, 2023.
Results: Most fluid collections treated with percutaneous drain placement were secondary to ipsilateral breast surgery (92%, 44/48), most commonly breast reduction (23%, 10/44) and mastectomy with immediate tissue expander reconstruction (16%, 7/44).
[Racial inequality in the production of fresh vegetables and cut flowers in Argentina: an analysis in Greater La Plata].
Salud Colect
December 2024
Licenciada en Ciencias Antropológicas. Becaria Doctoral, Consejo Nacional de Investigaciones Científicas y Técnicas, con sede en el Centro de Estudios en Nutrición y Desarrollo Infantil, Buenos Aires, Argentina.
This study aims to analyze the configuration of inequalities in one of Argentina's most significant production zones for fresh vegetables and cut flowers, located in Greater La Plata, Buenos Aires Province. This ongoing anthropological research, initiated in 2021, employs methods such as participant observation, interviews, food mapping, and digital ethnography. Among the main findings, we highlight that this production zone exhibits, in both its origins and daily operations, certain racist dynamics that are not solely generated by the host society toward migrants but are disseminated throughout the social fabric, including by migrant producers themselves.
View Article and Find Full Text PDFInfluences of maternal reflective functioning on adolescents' psychosocial adjustment: The mediating role of adolescent's reflective functioning.
PLoS One
December 2024
Department of Educational Psychology, Seoul Women's University, Seoul, Republic of Korea.
This study examines the relationship between maternal reflective functioning and adolescents' reflective functioning and psychosocial adjustment. In Study 1, The Parental Reflective Functioning Questionnaire for Adolescents (PRFQ-A) and Reflective Functioning Questionnaire for Youth (RFQ-Y), multidimensional scales used to assess reflective functioning in parents and adolescents, respectively, were validated in groups of Korean adolescents and mothers. In the results, the three factors were extracted (non-mentalizing, certainty, interest/curiosity) that were similar to those from the original version of the scale.
View Article and Find Full Text PDFResearch on using Aquilaria sinensis callus to evaluate the agarwood-inducing potential of fungi.
PLoS One
December 2024
Key Laboratory of National Forestry and Grassland Administration for Control of Diseases and Pests of South Plantation, Central South University of Forestry and Technology, Changsha, China.
Agarwood is a precious resinous heartwood highly valued for its cultural, religious, and medicinal significance. With the increasing market demand, natural agarwood resources are rapidly depleting, making the development of effective artificial induction methods for agarwood highly significant. This study aims to explore the feasibility of using callus tissue to assess the ability of fungi to induce agarwood formation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!