Obesity is a pandemic disease that poses a serious problem for the entire world population. Preventative and non-pharmacological treatments for obesity include changing eating habits and increasing physical activity. The use of certain dietary supplements also brings beneficial results in the process of reducing excess body weight. There are many options for the treatment of obesity available on the pharmaceutical market. This study aims to review the latest publications on selected dietary supplements in the treatment of excess body weight. Dietary supplements which support a reduction in excess body weight include capsaicin, bitter orange, white bean seeds, green coffee, berberine, and single and multi-strain probiotics. Some of these supplements have additional health benefits. Bitter orange has antioxidant and anti-ulcer properties. Berberine improves lipid metabolism and reduces blood glucose levels. Capsaicin has found application in the treatment of neurodegenerative diseases. Supplements that do not significantly reduce body weight are chitosan and vitamin D. Chitosan can reduce blood pressure, while vitamin D improves the sensitivity of tissue to insulin. An increase in body mass index (BMI) is associated with an increased risk of many diseases, including cardiovascular disease, diabetes mellitus, musculoskeletal disorders, and certain cancers. Dietary supplements with beneficial effects which support a reduction in excess body weight can be used in the treatment of both obesity and its complications.
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http://dx.doi.org/10.17306/J.AFS.1010 | DOI Listing |
Gut Microbes
December 2025
Gastroenterology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Irritable bowel syndrome (IBS) is a multifactorial condition with heterogeneous pathophysiology, including intestinal permeability alterations. The aim of the present study was to assess the ability of a probiotic blend (PB) consisting of two strains (CECT7484 and CECT7485) and one strain of (CECT7483) to recover the permeability increase induced by mediators from IBS mucosal biopsies and to highlight the underlying molecular mechanisms. Twenty-one IBS patients diagnosed according to ROME IV criteria (11 IBS-D and 10 IBS-M) and 7 healthy controls were enrolled.
View Article and Find Full Text PDFHistol Histopathol
January 2025
Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, India.
Autism spectrum disorder (ASD) is a globally recognized neurodevelopmental condition characterized by repetitive and restrictive behavior, persistent deficits in social interaction and communication, mental disturbances, etc., affecting approximately 1 in 100 children worldwide. A combination of genetic and environmental factors is involved in the etiopathogenesis of the disease, but specific biomarkers have not yet been identified.
View Article and Find Full Text PDFHeliyon
July 2024
Department of Biosystems and Technology, Swedish University of Agricultural Sciences, 23456, Alnarp, Sweden.
Monoterpenoids are interesting hydrocarbons typically found in essential oils and have a significant role in medicinal and biological purposes. The goal of this study was to investigate the effects of two monoterpenoids, carvacrol (CAR) and menthol (MEN), supplemented with leaf meal (MOLM) based diets on growth parameters, digestibility and body composition of Nile tilapia (). Alongside the basal diet (control-T1), nine experimental diets supplemented with categorized levels of CAR and MEN at 200, 300 and 400 mg/kg individually and their mixtures (MIX) (1:1) (CAR-T2, 200; T3, 300; T4, 400 mg/kg, MEN-T5, 200; T6, 300; T7, 400 mg/kg and MIX- (1:1) T8, 200; T9, 300; T10, 400 mg/kg) were fed to the fingerlings (6.
View Article and Find Full Text PDFNarra J
December 2024
Department of Animal Production and Technology, Faculty of Animal Science, Institut Pertanian Bogor, Bogor, Indonesia.
Previous studies of IIA-1A5 have shown its potential as a probiotic in modulating gut microbiota and providing health benefits; however, its effects during pregnancy remain underexplored. The aim of this study was to assess the safety of fermented milk enriched with IIA-IA5 in pregnant mice. An experimental study was conducted at Universitas Andalas, Padang, Indonesia.
View Article and Find Full Text PDFNarra J
December 2024
Department of Internal Medicine, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
The coexistence of depression and type 2 diabetes mellitus (T2DM) can significantly worsen disease prognosis and lower quality of life. Emerging evidence suggests that vitamin D deficiency contributes to the progression of T2DM and is closely associated with the development of depression. The aim of this study was to investigate the effects of cholecalciferol on depression in patients with T2DM, exploring its mechanisms by analyzing its impact on C-peptide, serotonin, and neurotrophin-3 levels.
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