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Block design stimulus variables (perceptual cohesiveness, response uncertainty, partial components) have been previously shown to impact test performance. However, relevant studies suggest designs that "look" different should elicit similar performance, where these stimulus parameters are identical. The current study sought to explore other, previously unidentified parameters. To control for known parameters, designs with no perceptual cohesiveness and maximum uncertainty were presented-rotated in increments of 90° and with block edges either cued or uncued-to 65 university undergraduates. Even with cohesiveness and uncertainty constant, performance differences between designs that "look" different were elicited. Post hoc, we hypothesized two possible contributory parameters and coded the designs accordingly. Regression analysis suggested redundancy of adjacent blocks (i.e., coherent regions within the design) appeared to reduce the actual uncertainty of some designs. On the other hand, local and global symmetry, as defined by Palmer (1991, The Perception of Structure, pp. 23-39, The American Psychological Association), did not seem to predict block design performance above and beyond the effects of coherent regions. The advantages of a more complete understanding of stimulus contributions to test performance are discussed.
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http://dx.doi.org/10.3758/s13414-021-02396-w | DOI Listing |
Adv Mater
December 2024
David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Immune reactions to medical implants often lead to encapsulation by fibrotic tissue and impaired device function. This process is thought to initiate by protein adsorption, which enables immune cells to attach and mount an inflammatory response. Previously, several antifibrotic materials have been either designed to reduce protein adsorption or discovered via high-throughput screens (HTS) to favorably regulate inflammation.
View Article and Find Full Text PDFBMC Plant Biol
December 2024
College of Horticulture, Hebei Agricultural University, Baoding, 071001, China.
Light conversion films are crucial for optimizing vegetable crop production in greenhouses, particularly during winter and spring seasons. This study investigated the effects of a europium-based light conversion film (RPO) compared to traditional polyolefin film (PO film, control) on cucumber (Cucumis sativus L.) cultivation, focusing on handle length, yield, and fruit quality in a randomized complete block design with three replications.
View Article and Find Full Text PDFBioorg Chem
December 2024
Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 210000, China. Electronic address:
The non-specificity of F-FDG, coupled with high false-positive rates in pancreatitis, underscores an unmet clinical need for using specific positron emission tomography (PET) radiopharmaceuticals in noninvasive pancreatic cancer detection. ST14, a trypsin-like protease and a member of the type II transmembrane serine protease family, is overexpressed in various solid malignancies, including pancreatic cancer. This study aimed to develop a Ga-labeled PET radiopharmaceutical targeting ST14 for pancreatic cancer detection.
View Article and Find Full Text PDFEur J Med Chem
December 2024
College of Chemistry and Materials Science, Zhejiang Normal University, No. 688 Yingbin Road, Jinhua, Zhejiang Province, 321004, China; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education, College of Pharmacy, Jinan University, No. 601 Huangpu Avenue West, Guangzhou, 510530, China. Electronic address:
Right open reading frame kinase 2 (RIOK2) is an atypical serine threonine kinase which plays an important role in regulating ribosome synthesis and cell cycle progression. RIOK2 has been implicated in multiple human cancers and is a potential target for cancer treatment. We previously reported the discovery of CQ211 as a potent and selective RIOK2 inhibitor.
View Article and Find Full Text PDFACS Nano
December 2024
State Key Laboratory of Material Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Surface engineering is sought to stabilize nickel-rich layered oxide cathodes in high-energy-density lithium-ion batteries, which suffer from severe surface oxygen loss and rapid structure degradation, especially during deep delithiation at high voltages or high temperatures. Here, we propose a well-designed oxygen-constraining strategy to address the crisis of oxygen evolution. By integrating a La, Fe gradient diffusion layer and a LaFeO coating into the Ni-rich layered particles, along with incorporating an antioxidant binder into the electrodes, three progressive lines of defense are constructed: immobilizing the lattice oxygen at the subsurface, blocking the released oxygen at the interface, and capturing the residual singlet oxygen on the external surface.
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