Vitex, the genus of the family Lamiaceae, comprises of about 230 species mostly distributed in the warm regions of Europe and temperate regions of Asia. Several Vitex species have been used as folk medicine in different countries for the treatment of various kinds of diseases and ailments. The main aim of this review is to collect and analyze the scientific information available about the Vitex species regarding their chemical constituents and pharmacological activities. The phytochemical investigation of various Vitex species has resulted in the isolation of about 556 chemical constituents belong to various chemical category viz. iridoids, diterpenoids, triterpenoids, flavonoids, lignans, sesquiterpenoids, monoterpenoids, ecdysteroids, and others. The crude extracts of different Vitex species as well as pure phytochemicals exhibited a wide spectrum of in-vitro and in-vivo pharmacological activities. In the present review, the scientific literature data on the ethnopharmacological, phytochemical, and pharmacological investigations on the genus Vitex are summarized. More attention should be given in future research to evaluate the pharmacological potential with detailed mechanism of actions for the pure compounds, extracts of plants from this genus. Moreover, their clinical study is needed to justify their use in modern medicine and to further exploring this genus for new drug discovery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ptr.7330 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Insights into the Genomic Background of Nine Common Chinese Medicinal Plants by Flow Cytometry and Genome Survey.
Plants (Basel)
December 2024
Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Haixia Institute of Science and Technology, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Medicinal plants have long played a crucial role in healthcare systems, but limited genomic information on these species has impeded the integration of modern biological technologies into medicinal plant research. In this study, we selected nine common medicinal plants, each belonging to a different plant family, including (Chloranthaceae), (Vitaceae), (Fabaceae), (Cucurbitaceae), (Polygonaceae), (Caryophyllaceae), (Rubiaceae), (Lamiaceae), and (Asteraceae), to estimate their genome sizes and conduct preliminary genomic surveys. The estimated genome sizes by flow cytometry were 3.
View Article and Find Full Text PDFBioactive Phytophenolics of Vitex negundo Reveal Therapeutic Antifungal Potentials against Candida albicans.
Chin J Integr Med
November 2024
Department of Biotechnology, National Institute of Technology, Raipur, CG, 492010, India.
Objective: To map the potent antifungal properties of the medicinal plant Vitex negundo, in vitro and in silico studies were performed to decipher the pharmacokinetics and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) properties of their phytoconstituents.
Methods: With the PASS (Prediction of Activity Spectra for Substances) prediction tool, many parameters of V. negundo phenolics were examined, including drug-likeness, bioavailability, antifungal activity, and anti-biofilm activity.
Repellent activity of Vitex negundo and Curcuma longa herbal extract against Simulium species in India.
J Vector Borne Dis
July 2024
Department of Entomology, Defence Research Laboratory (DRDO), Tezpur, Assam, India.
Background Objectives: At present, use of synthetic pesticides to manage insects and other arthropods creates a number of issues that are related to the environment and public health. The goal of the present study is to find repellent activity of Vitex negundo and Curcuma longa herbal extracts against the wild species Simulium (blackfly) bite.
Methods: We have studied Simulium biting behavior and tested the repellency of herbal extract obtained from Vitex negundo L.
Performance of vertical flow constructed wetland for the treatment of effluent from a brassware industry in city of Fez, Morocco: a laboratory scale study.
Int J Phytoremediation
July 2024
Higher Institute of Nursing and Health Technical, Meknes, Morocco.
Brassware industry constitutes the second most polluting industrial sector in Fez city, Morocco, owing to its high heavy metal load. The aim of this study is to examine and evaluate the performance of vertical flow constructed wetlands in treating brassware effluents using various plant species. Ten treatment systems were planted with four types of plants: , , and , while another system remained unplanted.
View Article and Find Full Text PDFThe dynamics of nocturnal sap flow components of a typical revegetation shrub species on the semiarid Loess Plateau, China.
Front Plant Sci
March 2024
Key Research Institute of Yellow Civilization and Sustainable Development and Collaborative Innovation Center of Henan Province, Henan University, Kaifeng, China.
Article Synopsis
- The study examines nighttime sap flux components, including transpiration and stem water recharge, and their impact on water balance and drought adaptation in plant communities on the Loess Plateau.
- Using the heat balance method, researchers measured sap flow density in a normal and a wetter precipitation year (2021 and 2022), finding both transpiration and stem water recharge were higher in the wetter year.
- Results indicate that soil water content is a major factor influencing transpiration and stem recharge on a monthly basis, while meteorological factors have less impact on daily variability, offering insights into plant responses to climate change and drought conditions.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!