Appendiceal cancers may be difficult to diagnose even after comprehensive investigation. This report of locally advanced perforated appendiceal adenocarcinoma attached to the terminal ileum, cecum, and rectosigmoid illustrates the management challenges that require comprehensive knowledge of pathologic variations and range from simple appendectomy to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832381PMC
http://dx.doi.org/10.1002/ccr3.5349DOI Listing

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