The differential diagnosis of abdominal pain is wide as both benign and malignant pathologies must be considered. There are currently no published case reports of low-grade appendiceal mucinous neoplasms (LAMNs) mimicking perforated diverticulitis. LAMNs are a heterogenous group of tumours, with no consensus treatment algorithm based on stage and histology. In this case report, we discuss a patient who presented emergently with generalized peritonism, with a diagnosis of perforated diverticulitis made on computed tomography scan. At laparotomy, a perforated appendix was identified, with histopathology identifying a perforated LAMN. This case highlights the importance of considering this rare but increasing incidence tumour when operative management is being planned.
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http://dx.doi.org/10.1093/jscr/rjac014 | DOI Listing |
J Med Case Rep
January 2025
Director of Hospital Pharmacy, Santa Croce e Carle Hospital, Cuneo, Italy.
Background: Mantle cell lymphoma is a diverse B-cell lymphoma with varying clinical behaviors. Treating relapsed or refractory mantle cell lymphoma is challenging, with Bruton's tyrosine kinase inhibitors proving effective but not curative. Post-Bruton's tyrosine kinase inhibitor failure, the prognosis remains unfavorable.
View Article and Find Full Text PDFTech Coloproctol
January 2025
Epidemiology, IQVIA, 60549, Frankfurt, Germany.
Background: This study aims to evaluate the current rates and outcomes of minimally invasive versus open surgery for colonic diverticular disease in Germany, using a nationwide dataset.
Methods: We analyzed data from 36 hospitals, encompassing approximately 1.25 million hospitalizations from 1 January 2019 to 31 December 2023.
Radiol Case Rep
March 2025
Department of General Surgery, Trauma and Burns Center, University of Tunis El Manar, Ben Arous, Tunisia.
Meckel's diverticulum, a congenital anomaly of the omphalomesenteric duct, is a rare cause of acute abdomen and poses significant diagnostic challenges due to its variable presentation and complications such as perforation. We present the case of a 19-year-old male with a 24-hour history of right iliac fossa pain progressing to generalized abdominal tenderness. Laboratory results showed leukocytosis and elevated C-reactive protein, while CT imaging suggested pneumoperitoneum and an inflamed Meckel diverticulum.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
: To evaluate the non-inferiority of non-contrast CT compared to contrast-enhanced CT with both intravenous and rectal contrast application for the diagnosis of acute colonic diverticulitis. : Five readers retrospectively evaluated the non-contrast and contrast-enhanced series of CTs of 205 consecutive patients with clinical suspicion of acute diverticulitis. Two randomized reading sessions, both containing all 205 cases as either contrast-enhanced or non-contrast (1:1) series, were performed with ≥8 weeks washout between them.
View Article and Find Full Text PDFCureus
December 2024
Department of Surgery, Faculty of Medicine and Health Science, Sana'a University, Sana'a, YEM.
Introduction Anastomotic leakage (AL) following stoma closure is a significant complication that can lead to increased morbidity and mortality. Identifying risk factors associated with AL is essential for improving surgical outcomes, especially in resource-limited settings like Yemen. Methods We conducted this retrospective study at Al-Thawra Modern General Hospital and the Republican Teaching Hospital Authority in Sana'a, Yemen, between August 2020 and April 2024.
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