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Efficacy and safety of pharmacological treatments in inclusion body myositis: a systematic review.
RMD Open
January 2025
Department of Neuromuscular Diseases, University College London, London, UK
Objective: To identify the best evidence on the efficacy of treatment interventions for inclusion body myositis (IBM) and to describe their safety.
Methods: Systematic review of randomised controlled trials (RCTs) of pharmacological treatments of adults with IBM, conducted according to the Cochrane Handbook, updating a previous Cochrane review. The search strategy was run on Cochrane Neuromuscular Disease Group Specialized Register, CENTRAL, MEDLINE and EMBASE, ClinicalTrials.
Concussion in high school sports: findings from injury surveillance.
Pediatr Res
January 2025
Datalys Center for Sports Injury Research and Prevention, Indianapolis, IN, USA.
Background: We aimed to examine the epidemiology of concussions within high school (HS) boys' and girls' sports, and to assess the incidence of concussion within HS sports during the timespan inclusive of the COVID-19 pandemic.
Methods: We analyzed data captured within High School Reporting Information Online (HS RIO) during 2018/19-2022/23. Injury counts, rates (enumerated per 10,000 athlete-exposures (AEs)), and proportions were used to describe injury characteristics by sport, event type, injury mechanism, and injury history.
Current Trends in Virtual Exercise Interventions Among People With Disabilities: A Scoping Review.
Arch Rehabil Res Clin Transl
December 2024
Division of Pediatric Rehabilitation Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL.
Objective: To analyze existing literature on virtual exercise interventions delivered to people with disabilities to assess effectiveness, efficiency, usability, satisfaction, and feasibility, and describe current trends that aimed to improve health outcomes among people with disabilities.
Data Sources: CINAHL, MEDLINE, and PsycINFO were searched.
Study Selection: Articles were included if they were (1) incorporated a virtual exercise intervention including people with physical disabilities and mobility limitations aged 18 years and older and (2) published between the years of 2009-August 14, 2024 with free access to full-text, peer-reviewed papers; and (3) published in English.
Respiratory failure as main presentation sign of MAPT-related disorder.
J Neurol
January 2025
Centre de Génétique Humaine, Centre Hospitalier Universitaire de Besançon, Besançon, France.
Introduction: The MAPT gene encodes Tau, a protein mainly expressed by neurons. Tau protein plays an important role in cerebral microtubule polymerization and stabilization, in axonal transport and synaptic plasticity. Heterozygous pathogenic variation in MAPT are involved in a spectrum of autosomal dominant neurodegenerative diseases known as taupathies, including Alzheimer's disease, Pick's disease, fronto-temporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
View Article and Find Full Text PDFSkin cancer treatment environment and survivorship resources among sexual and gender minority patients: results of the OUT National Cancer Survey.
Arch Dermatol Res
January 2025
Department of Dermatology, Emory University School of Medicine, Atlanta, GA, USA.
Sexual and gender minority (SGM) cancer survivors face unmet care needs in accessing cancer health information and social support despite high satisfaction with treatment. SGM patients often delay care due to concerns of discrimination in healthcare settings, though the care experiences of SGM skin cancer survivors are less known. SGM individuals, particularly sexual minority men, report higher skin cancer prevalence and related risk behaviors than heterosexual men.
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