Management of Children with Reported Penicillin Allergies.

Infect Dis Clin North Am

Department of Pediatrics, Division of Infectious Diseases, Pediatric Infectious Diseases, Medical College of Wisconsin, Children's Corporate Center, Suite C450, 999 North 92nd Street, Milwaukee, WI 53226, USA.

Published: March 2022

AI Article Synopsis

  • Penicillin allergy is the most frequently reported drug allergy, leading to higher health risks for patients.
  • Risk assessment tools can guide the best testing methods to confirm or refute the allergy for individuals.
  • Effective strategies, like oral challenges for low-risk individuals and skin tests for high-risk ones, must be supported by interventions, such as updating electronic health records, to ensure accurate allergy status is communicated.

Article Abstract

Penicillin allergy is the most commonly reported medication allergy. Reported allergy is associated with increased morbidity and mortality. Risk categorization tools can help determine the optimal testing strategies to delabel patients with reported allergy. Approaches to allergy removal include oral challenge in low-risk patients and skin testing in high-risk patients. Many different locations may be used to test for allergy, including ambulatory care clinics, inpatient units, and emergency departments. Interventions (eg, use of the electronic medical record) are needed to ensure that once the allergy is removed, this information is effectively transmitted to the patient and appropriate providers.

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Source
http://dx.doi.org/10.1016/j.idc.2021.11.001DOI Listing

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