Purpose: This study aimed to validate the World Society for Emergent Surgery (WSES) scale for the management of acute left-sided colonic diverticulitis (ALCD).
Methods: An observational study based on a prospective database of patients with ultrasound (US) and computerized tomography (CT) confirmed ALCD was conducted at our center from April 2018 to May 2019. The primary outcome was the success rate of outpatient management. Secondary outcomes were the association between different WSES stages, clinical and analytical parameters, treatments modalities, and outcomes, and the accuracy of US for management decisions.
Results: A total of 230 patients were included. Outpatient management was successful in 51/53 (96.23%) cases with ALCD stage 0 and 62/72 (86.11%) patients with stage 1A. There were no differences in age (p = 0.076) or the presence of pericolic air bubbles (p = 0.06) between patients who underwent admission or outpatient management. Clinical and analytical data, treatment decisions, and outcomes showed statistically significant differences between WSES stages. In 7/12 patients with stage 2A, percutaneous drainage or emergency surgery was required. All cases with stage 2B (distant air) underwent conservative management without the need for emergency or elective surgery. The accuracy of US WSES stages for management decisions, when compared with CT, was 96.96%.
Conclusion: The WSES classification for ALCD seemed to be valid helping clinicians in the decision-making process to select between admission or outpatient management. Differences in clinical and analytical data, elected treatments, and outcomes were found between WSES stages. The US WSES stages showed high accuracy for management decisions.
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http://dx.doi.org/10.1007/s00068-022-01911-4 | DOI Listing |
Sci Rep
January 2024
Catholic University of the Sacred Heart, Largo F. Vito, 1, 00168, Rome, Italy.
Left-sided acute diverticulitis in WSES Stage 0-IIb preferentially undergoes conservative management. However, there is limited understanding of the risk factors for failure of this approach. The aim of this study was to investigate the factors associated with the decision to perform conservative treatment as well as the predictors of its failure.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2023
Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University Hospital Policlinico "G. Rodolico-San Marco", 95123 Catania, Italy.
Crit Care Nurs Clin North Am
September 2022
Louisiana State University Health Sciences Center New Orleans. Electronic address:
The liver is the most frequently damaged organ in abdominal trauma. There is a high risk of hemorrhage and mortality as severity of injury and stage increases. During the last decade, management of liver trauma standards changed when the American Association of the Surgery of Trauma adjusted their guidelines to focus on early computed tomography scanning to determine the severity of liver injury trauma and the need for surgical verses nonsurgical management.
View Article and Find Full Text PDFSci Rep
August 2022
Chair of Food Biochemistry, Faculty of Food Science, University of Warmia and Mazury in Olsztyn, Pl. Cieszyński 1, 10-719, Olsztyn-Kortowo, Poland.
This study is the first to present an integrated approach involving in silico and in vitro protocols that was pursued to analyse an antioxidative potency of Gouda cheese with modified content of β-casein. Firstly, the predictions of the presence of antioxidant peptides in the casein sequences were computed using the BIOPEP-UWM database. Then, the antioxidative bioactivity of six variants of Gouda cheese (with reduced, normative, and increased content of β-casein at the initial and final stage of ripening) was assessed.
View Article and Find Full Text PDFEur J Trauma Emerg Surg
October 2023
Department of Emergency Surgery, Parma University Hospital, Parma, Italy.
Background: The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease.
Aim: To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis.
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