AI Article Synopsis
- Peptide drug development has advanced significantly in the last ten years due to new technologies that improve production, modification, and analysis.
- Both chemical and biological methods have been used to produce and modify peptides, enhancing their effectiveness and enabling new delivery strategies.
- The review highlights current achievements in the field, including applications across various therapeutic areas, while also addressing future challenges and opportunities in peptide therapy.
Article Abstract
Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. Peptides have been produced and modified using both chemical and biological methods, together with novel design and delivery strategies, which have helped to overcome the inherent drawbacks of peptides and have allowed the continued advancement of this field. A wide variety of natural and modified peptides have been obtained and studied, covering multiple therapeutic areas. This review summarizes the efforts and achievements in peptide drug discovery, production, and modification, and their current applications. We also discuss the value and challenges associated with future developments in therapeutic peptides.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844085 | PMC |
| http://dx.doi.org/10.1038/s41392-022-00904-4 | DOI Listing |
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