Increased cardiac uptake of (F)-fluorodeoxyglucose incidentally detected on positron emission tomography after left breast irradiation: How to interpret?

Cancer Radiother

Department of Medical Oncology, Institut de cancérologie Strasbourg Europe (ICANS), 17, rue Albert-Calmette, BP 23025, 67033 Strasbourg, France.

Published: September 2022

Radiation-induced heart disease is a complication that occurs years after thoracic irradiation. Recent studies suggest that radiation-induced heart disease could be an earlier complication and that subclinical cardiac injury can be detected. The present case described an increased uptake of (F)-fluorodeoxyglucose incidentally detected on positron emission tomography after left breast irradiation with slightly reversible perfusion defect on (Tc)-tetrofosmin single photon emission computed tomography. The cardiac clinical examination was asymptomatic, and the patient had a normal angiography, suggesting a radiation-induced hibernating myocardium. The relevant question is: how far should an incidentally (F)-fluorodeoxyglucose uptake be explored?

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http://dx.doi.org/10.1016/j.canrad.2021.10.010DOI Listing

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