AI Article Synopsis
- Naudin, a plant species from the Cerrado, shows promise for therapeutic uses, prompting researchers to standardize its aqueous leaf extracts and examine seasonal chemical differences.
- Seven batches of extracts were analyzed for their total solids, polyphenolic content, flavonoids, and antioxidant activity using techniques like TLC and HPLC.
- The seasonal study, which spanned from May 2017 to August 2018, found that chemical compositions remain stable throughout the year, indicating that extracts can be consistently produced without major variations in quality.
Article Abstract
Naudin is a species from the Cerrado, which is being increasingly researched for its therapeutic potential. The aim of this study was to obtain a standardized extract and to evaluate seasonal chemical variations. Seven batches of aqueous extracts from leaves were produced for the standardization. These extracts were evaluated for total solids, polyphenol (TPC) and flavonoid content (TFC), vitexin derivative content, antioxidant activity; thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC) profiles were generated. For the seasonal study, leaves were collected from five different periods (May 2017 to August 2018). The results were correlated with meteorological data (global radiation, temperature, and rainfall index). Using chromatographic and spectroscopic techniques, apigenin C-glycosides (vitexin/isovitexin) and derivatives, luteolin C-glycosides (orientin/isoorientin) and derivatives, a quercetin glycoside, miconioside B, matteucinol-7--β-apiofuranosyl (1 → 6) -β-glucopyranoside, and farrerol were identified. Quality parameters, including chemical marker quantification by HPLC, and biological activity, are described. In the extract standardization process, all the evaluated parameters showed low variability. The seasonality study revealed no significant correlations ( < 0.05) between TPC or TFC content and meteorological data. These results showed that it is possible to obtain extracts from at any time of the year without significant differences in composition.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838837 | PMC |
| http://dx.doi.org/10.3390/molecules27031120 | DOI Listing |
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