Flavanols from Nature: A Phytochemistry and Biological Activity Review.

Molecules

TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.

Published: January 2022

AI Article Synopsis

  • Flavanols are plant metabolites known for their health benefits, including acting as antioxidants, anti-carcinogens, and neuroprotective agents, and they are also used as functional ingredients in dairy products.
  • This review compiles 121 different flavanols, categorizing them into four main types: flavan-3-ols, flavan-4-ols, isoflavan-4-ols, and flavan-3,4-ols.
  • The study aims to establish a foundation for future research on flavanols' structures and health effects, providing direction and inspiration for researchers in the field.

Article Abstract

Flavanols, a common class of secondary plant metabolites, exhibit several beneficial health properties by acting as antioxidant, anticarcinogen, cardioprotective, anti-microbial, anti-viral, and neuroprotective agents. Furthermore, some flavanols are considered functional ingredients in dairy products. Based on their structural features and health-promoting functions, flavanols have gained the attention of pharmacologists and botanists worldwide. This review collects and summarizes 121 flavanols comprising four categories: flavan-3-ols, flavan-4-ols, isoflavan-4-ols, and flavan-3,4-ols. The research of the various structural features and pharmacological activities of flavanols and their derivatives aims to lay the groundwork for subsequent research and expect to provide mentality and inspiration for the research. The current study provides a starting point for further research and development.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838462PMC
http://dx.doi.org/10.3390/molecules27030719DOI Listing

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