Application of Novel Pharmacists' Risk in Pharmacotherapy (PHARIPH) Scale for Identification of Factors Affecting the Safety of Hospital Pharmacotherapy-An Observational Pilot Study.

Background: The widespread occurrence of medication errors (MEs) has become a global problem because it poses a serious threat to the health and lives of patients, can prevent the achievement of treatment goals, undermines patient trust in the health care system, and increases treatment costs. The purpose of this study was to develop an appropriate tool to identify key risk factors that hospital pharmacists believe threaten pharmacotherapy safety in the hospital.

Methods: A diagnostic survey method using the authors' PHARIPH (Pharmacists' Risk in Pharmacotherapy) scale and authorial questions was used to identify risks that may result in patient pharmacotherapy errors at the hospital pharmacist level. A total of 125 Polish hospital pharmacists participated in the study.

Results: The original authors' created PHARIPH scale was characterized by a Cronbach's alpha coefficient of 0.958. According to the surveyed pharmacists, the greatest threat to pharmacotherapy safety was misreading of a doctor's order (similar drug nomenclature) and preparing a wrong drug (similar drug packaging, similar drug nomenclature). Female pharmacists compared to male pharmacists attributed significantly higher importance to such risk factors such as pharmacist's ignorance of a list of drug substitutes ( = 0.047, risk 8), preparation from an expired/withdrawn drug ( = 0.002, risk 14), preparation from a drug stored in inappropriate conditions ( = 0.05, risk 15), preparation of drugs ordered in hospital and PODs (patients' own drugs) without checking for possible drug duplication ( = 0.011, risk 17) and their potential effect on patient safety.

Conclusions: The PHARIPH scale could be applied as a novel tool for identification of pharmacotherapy risks.