The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children.

J Clin Med

Department of Otolaryngology, Phoniatrics and Audiology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 85-168 Bydgoszcz, Poland.

Published: January 2022

AI Article Synopsis

  • The study investigates the long-term effects of a 12-week course of topical steroids on adenoid size, mucus, and middle ear effusion in children.
  • Three to six months post-treatment, no significant changes in adenoid size, mucus coverage, or tympanograms were observed, indicating that the steroids had no lasting impact.
  • The findings suggest that if surgery (adenoidectomy or tympanostomy) is needed, it should not be delayed based on the use of topical steroids.

Article Abstract

Background: The purpose of this study is to analyse the long-term effects of a 12-week course of topical steroids on adenoid size and its mucus using endoscopy and on middle ear effusion measured by tympanometry.

Methods: The study presents an endoscopic choanal assessment of the change in adenoid size (adenoid to choanae ratio, A/C ratio) and its mucus coverage in 165 children with Grade II and III adenoid hypertrophy three to six months after finishing a 12-week course of intranasal steroid treatment with mometasone furoate. Additionally, tympanometry was performed to measure middle ear effusion. Changes in the tympanograms were analysed.

Results: The mean A/C ratio before treatment was 65.73%. Three to six months after finishing a 12-week course of intranasal steroid treatment, the mean A/C ratio decreased to 65.52%, although the change was not statistically significant ( = 0.743). There was no change in adenoid mucus according to the MASNA scale before and three to six months after the end of the steroid treatment ( = 0.894). Long-term observations of tympanograms before and three to six months after the end of the treatment did not show improvement ( = 0.428).

Conclusions: The results indicate that there was no effect of topical steroids on adenoid size, its mucus and otitis media with effusion (OME) three to six months after finishing a 12-week course of treatment. In the light of performed study, decision of adenoidectomy and tympanostomy should not be procrastinated.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836378PMC
http://dx.doi.org/10.3390/jcm11030507DOI Listing

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