AI Article Synopsis
- Phenolic compounds found in leaves have health benefits and were optimized for extraction in this study using ultrasonic-assisted techniques.
- The study used Box-Behnken design to identify ideal conditions for extracting these compounds, determining the best combination of 40% ethanol, a 1/400 solvent/sample ratio, and 35 minutes of extraction time.
- The extraction yielded 21 phenolic compounds, including protocatechuic acid-glucoside, caffeoylquinic acid, and flavonols like quercetin-3-O-6-acetylglucoside and rutin, which comprised over 7% of the total phenolic content.
Article Abstract
Phenolic compounds of leaves are bioactive compounds with beneficial properties for human health. Therefore, in this study, an optimization of ultrasonic assisted extraction by Box-Behnken design was used for the first time to optimize factors such as the percentage of ethanol, ratio solvent/sample (/) and extraction time to reach the highest phenolic compound amounts (evaluated by HPLC-MS) while also evaluating in vitro antioxidant activity using DPPH, ABTS and FRAP assays. The optimal extraction conditions were 40% ethanol, 1/400 (/) and 35 min. Applying these optimal conditions, which were identified and quantified by HPLC-MS, resulted in the extraction of 21 phenolic compounds. According to these results, the main phenolic compounds in leaves are the phenolic glycoside and phenolic acid named protocatechuic acid-glucoside and caffeoylquinic. In addition, leaf extract contains flavonols such quercetin-3-O-6-acetylglucoside and rutin, which represent more than 7% of its total phenolic content.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834592 | PMC |
| http://dx.doi.org/10.3390/foods11030314 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lacto-Fermented Fruits and Vegetables: Bioactive Components and Effects on Human Health.
Annu Rev Food Sci Technol
January 2025
1Department of Food Science and Technology, University of California, Davis, Davis, California, USA; email:
Lacto-fermented fruits and vegetables (FVs) such as kimchi, sauerkraut, and fermented olives and nonalcoholic juices have a long history as dietary staples. Herein, the production steps and microbial ecology of lacto-fermented FVs are discussed alongside findings from human and laboratory studies investigating the health benefits of these foods. Lacto-fermented FVs are enriched in bioactive compounds, including lactic and acetic acids, phenolic compounds, amino acid derivatives such as indole-3-lactic acid, phenyl-lactic acid, γ-aminobutyric acid, and bacteriocins, and beneficial live microbes.
View Article and Find Full Text PDFFatty acid composition, total phenolic and total flavonoid contents, and antioxidant activity of Niger seed (Guizotia abyssinica) accessions collected from major producer areas of Ethiopia.
PLoS One
January 2025
Department of Chemistry, College of Natural and Computational Science, Debre Tabor University, Debre Tabor, Ethiopia.
Background: Oils from various sources are vital nutritional components with a variety of roles in our body. Niger seed (Guzoita abyssinica) is endemic to Ethiopia and is among the major oil seed crops grown in the country. The fatty acid composition and the concentration of other bioactive phytochemicals in it vary with species type, geographical origin, cultivation season, and varietal types.
View Article and Find Full Text PDF"Exploring the Potential of Ferulic Acid loaded Nanostructured Lipid Carriers: Angiotensin Inhibition via Docking, Formulation, and Pharmacokinetic and Pharmacodynamics Studies".
J Drug Target
January 2025
Department of Pharmaceutics, Sinhgad College of Pharmacy, Vadgaon (Bk.), Pune-411041, Maharashtra, India.
Ferulic acid (FA) is a phenolic compound obtained naturally and is a versatile antioxidant identified for its potential in managing hypertension. However, its application is constrained due to its classification as a BCS Class IV moiety. To address this, we concentrated on improving its solubility and permeability by developing nanostructured lipid carriers (NLCs) of FA using emulsification probe sonication technique.
View Article and Find Full Text PDFIntegrated of Hyperspectral Imaging and Machine Learning Algorithms for Nondestructive Detection of Therapeutic Properties of Plants.
Chem Biodivers
January 2025
Department of Horticultural Science, Faculty of Agriculture, Jahrom University, Jahrom, Iran.
The approaches used to determine the medicinal properties of the plants are often destructive, labor-intensive, time-consuming, and expensive, making it impossible to analyze their quality analysis online. Performance of hyperspectral imaging (HSI) integrated with intelligent techniques to overcome these problems was investigated in this research. For this purpose, three classification methods-support vector machine, random forest (RF), and extreme gradient boosting-were studied for the classification of plants in three classes of medicinal, edible, and ornamental for the organs of leaf, stem, flower, and root.
View Article and Find Full Text PDFPhytochemical Profiling and Biological Activities of Nigella sativa Vinegar Extract: An Insight Into Hypoglycemic Potential Using In Vivo and In Silico Studies.
Chem Biodivers
December 2024
Department of Biochemistry, Government College Women University, Faisalabad, Pakistan.
The current study was conducted to characterize the vinegar extract of Nigella sativa and evaluate its biological activities using in vitro and in vivo studies. The N. sativa extract (NSE) was prepared by macerating seeds in a mixture of water and synthetic vinegar (1:10).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!