AI Article Synopsis
- Methamphetamines, a type of stimulant drug, are becoming more common and pure, leading to an increase in methamphetamine-associated cardiomyopathy (MAC), which is linked to serious heart issues and poor health outcomes.
- Patients with MAC tend to be younger and face multiple health challenges compared to those with other types of heart disease, complicating their treatment.
- Effective management of MAC includes creating personalized treatment plans focused on stopping methamphetamine use, optimizing heart failure treatment, and providing comprehensive support to improve patient outcomes.
Article Abstract
Methamphetamines are illicit drugs of the amphetamine-type stimulant class that have been increasing in popularity, availability, and purity in recent decades. As a result, rates of methamphetamine-associated cardiomyopathy (MAC) are rising globally. MAC is associated with high rates of sudden cardiac arrest, late presentation, and poor outcomes. This review discusses the medical management of MAC, including anticipated challenges specific to methamphetamine users. Not only are patients with MAC more likely to present at a younger age and with multisystem disease than patients with cardiomyopathy of other etiologies, but there may also be significant behavioral, psychosocial, financial, and system-based challenges to providing the best medical care. An individualized treatment plan that emphasizes methamphetamine abstinence as the foundation of therapy, as well as introducing optimal heart failure therapy and providing multidisciplinary support is likely to result in optimal outcomes. Given the potential reversibility of MAC, institution of guideline-directed heart failure therapy and patient support for adherence to therapy and abstinence from methamphetamines should be energetically pursued.
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| http://dx.doi.org/10.1007/s40256-022-00523-y | DOI Listing |
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