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CLADES: A Programmable Cascade of Genes for Cell Lineage Analysis and Manipulation.
Methods Mol Biol
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Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
In the Drosophila brain, neuronal diversity originates from approximately 100 neural stem cells, each dividing asymmetrically. Precise mapping of cell lineages at the single-cell resolution is crucial for understanding the mechanisms that direct neuronal specification. However, existing methods for high-resolution lineage tracing are notably time-consuming and labor-intensive.
View Article and Find Full Text PDFCommunity case study: Our Wave, an online platform to facilitate survivor disclosure of sexual assault and trauma recovery.
Front Public Health
January 2025
Our Wave, Raleigh, NC, United States.
This community case study introduces Our Wave, an online platform that provides a safe, anonymous space for survivors of sexual harm to share their stories, reflect on their healing journeys, and connect with others. Designed to empower survivors, the platform allows users to post anonymous stories or visual media, ask questions, and send messages of hope, all while prioritizing privacy and security. It also aims to create a broader impact by analyzing shared narratives to detect patterns, identify best practices for healing, and inform global approaches to SV recovery.
View Article and Find Full Text PDFNutrient uptake and rhizosphere microbial community as related to yield advantage in broomcorn millet‒alfalfa intercropping under different row configurations.
BMC Plant Biol
January 2025
College of Grassland Agriculture, Northwest A&F University, Yangling, 712100, China.
To investigate the effects of row ratio configurations on intercropping advantages and related rhizosphere microbial communities, a field experiment involving five treatments of different rows of broomcorn millet, i.e., P1M1 (1 row of broomcorn millet intercropped with 1 row of alfalfa), P2M3, P1M2, P1M3 and broomcorn millet alone (SP), was conducted on the Loess Plateau of China.
View Article and Find Full Text PDFThe Role of Different Modalities of Regenerative Therapies in the Treatment of Erectile Dysfunction: A Global Survey and Global Andrology Forum Expert Recommendations.
World J Mens Health
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Department of Urology, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE.
Purpose: There is increased interest in regenerative therapies (RTs) to treat erectile dysfunction (ED). However, the need for society's guidelines has led to varied practices. This study aims to investigate current global practices, address the heterogeneity in treatment protocols and evaluations, and establish expert recommendations in clinical practice.
View Article and Find Full Text PDFEngraft: A Collaborative Learning Health Network for Enhanced Transplant and Cellular Therapy Outcomes.
Transplant Cell Ther
December 2024
University of Cincinnati College of Medicine, Cincinnati, Ohio; James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
The Engraft Learning Health Network (LHN) aims to improve outcomes for patients undergoing transplant and cellular therapy (TCT) through a collaborative, data-driven approach. Engraft brings together diverse stakeholders, including clinicians, patients, caregivers, and institutions, to standardize best practices and accelerate the dissemination of innovations in TCT care. By establishing a multicenter, real-world clinical registry focused on rapid-cycle quality improvement (QI) and implementation research, Engraft seeks to reduce variability in clinical practice to improve TCT outcomes across centers.
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