AI Article Synopsis

  • Over the past 21 years, orthopaedic publications have significantly increased in China compared to Japan and Korea, with China showing a mean annual growth of 35.5%.
  • A study using PubMed data analyzed publication trends from 1998 to 2020, revealing statistical significance in China's growth versus Japan and Korea.
  • The rise in Chinese publications may relate to the integration of Western medicine and digital health, while Japan and Korea's increases reflect improvements in their research environments.

Article Abstract

Introduction Over the past two decades, Asia has experienced the rise and integration of Western medicine and digital health in its field of medicine. In this study, we investigated the trends in orthopaedic publications from three Asian countries: China, Japan, and Korea. Methods PubMed was used to measure the number of publications from China, Japan, and Korea in the past 21 years, from 1998 to 2020. The average percentage change in publications during this 21-year time period was analyzed using descriptive statistics. The average annual change in the number of publications from each country was also determined. One-way analysis of variance and two-group t-tests were utilized for statistical analyses with a p-value of <0.05 as the cut-off value for statistical significance. Results From years 1998 to 2020, there was a mean 35.5% ± 70.7% annual increase in the number of total publications from China, in comparison to a 5.1% ± 14.0% annual increase from Japan (p = 0.005) and a 27.3% ± 40.0% annual increase from Korea (p = 0.586). Conclusion For the past two decades, there has been a strong positive trend regarding the total number of orthopaedic publications from China. This finding might be related in part to an increased integration of Western medicine and the use of digital medicine, which followed a similar trend during the time period we analyzed. Korea and Japan also exhibited a positive trend in orthopaedic publications, which may be indicative of an improving educational system and greater general support for research.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825441PMC
http://dx.doi.org/10.7759/cureus.21075DOI Listing

Publication Analysis

Top Keywords

china japan
8
japan korea
8
number publications
8
analysis eastern
4
eastern asia's
4
asia's contributions
4
contributions major
4
major orthopaedic
4
orthopaedic journals
4
journals years
4

Similar Publications

Cancer-associated fibroblasts (CAFs) are intrinsic components of the tumor microenvironment that promote cancer progression and metastasis. Through an unbiased integrated analysis of gastric tumor grade and stage, we identified a subset of proangiogenic CAFs characterized by high podoplanin (PDPN) expression, which are significantly enriched in metastatic lesions and secrete chemokine (CC-motif) ligand 2 (CCL2). Mechanistically, PDPN(+) CAFs enhance angiogenesis by activating the AKT/NF-κB signaling pathway.

View Article and Find Full Text PDF

Background: Therapeutic advancements for the polyglutamine diseases, particularly spinocerebellar degeneration, are eagerly awaited. We evaluated the safety, tolerability, and therapeutic effects of L-arginine, which inhibits the conformational change and aggregation of polyglutamine proteins, in patients with spinocerebellar ataxia type 6 (SCA6).

Methods: A multicenter, randomized, double-blind, placebo-controlled phase 2 trial (clinical trial ID: AJA030-002, registration number: jRCT2031200135) was performed on 40 genetically confirmed SCA6 patients enrolled between September 1, 2020, and September 30, 2021.

View Article and Find Full Text PDF

There is limited information on the occurrence of and ticks, as well as associated and species in Pakistan. Addressing this knowledge gap, the current study aimed at morphomolecular confirmation of these ticks and molecular assessment of associated Rickettsiales bacteria (, and spp.) in Balochistan, Pakistan.

View Article and Find Full Text PDF

The role of PPAR in fungal keratitis.

Front Immunol

January 2025

Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China.

The treatment of fungal keratitis(FK) remains challenging due to delayed fungal detection and the limited effectiveness of antifungal drugs. Fungal infection can activate both innate and adaptive immune responses in the cornea. Fungi stimulate the production of oxidative stress-related biomarkers and mediate the infiltration of neutrophils, macrophages, and T cells.

View Article and Find Full Text PDF

Chronic kidney disease (CKD) patients often suffer from complications such as anemia as the kidney function declines. More than 25% of CKD hemodialysis patients in China are complicated with renal anemia due to renal and hepatic impairment in the production of erythropoietin (EPO). In recent years, prolyl hydroxylase domain (PHD) inhibitors have been approved in China and Japan for the treatment of CKD patients complicated with anemia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!