AI Article Synopsis

  • Primary mucosal melanoma of the tonsil is rare, with only 27 reported cases, making accurate diagnosis crucial, as it’s often confused with metastatic melanoma.
  • A case study highlights a 31-year-old man with primary right tonsillar mucosal melanoma, who presented with neck lumps and was diagnosed after finding a pigmented lesion.
  • Due to the aggressive nature of this cancer and generally late diagnosis, treatment options are limited, focusing on local excision for early-stage disease and immunotherapy for advanced cases, leading to a poor prognosis.

Article Abstract

Primary mucosal melanoma of the tonsil is rare, with 27 reported cases. Careful diagnosis is necessary, as the tonsil is more often a site of metastatic melanoma from a cutaneous primary tumour. In this report, we present a case of primary right tonsillar mucosal melanoma with widespread metastasis in a 31-year-old man who presented with a 3-month history of enlarging neck lumps. On examination, he had cervical lymphadenopathy and a pigmented, vascular lesion of his right tonsil, which was diagnosed as melanoma following investigation. He had widespread metastases upon presentation, and is currently undergoing palliative immunotherapy. Owing to the aggressive behaviour, late presentations and lack of effective treatment to cure mucosal melanomas, they have a poor prognosis. Treatment involves wide local excision in local disease, and immunotherapy as the first-line for metastatic disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829020PMC
http://dx.doi.org/10.1093/jscr/rjac022DOI Listing

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