AI Article Synopsis
- The study aims to assess the annual healthcare costs related to obstetric events in women with immune-mediated inflammatory diseases (like psoriasis and rheumatoid arthritis) from the perspective of the National Healthcare System.
- A detailed cost-analysis was done to estimate expenses during fertility, pregnancy, and postpartum care, using validated parameters and relevant costs from national databases.
- Results showed significant costs associated with various complications; for instance, pregnancies complicated by conditions like preeclampsia and premature births led to extremely high hospital expenses, highlighting the economic impact of these health issues and the need for tailored treatments and monitoring.*
Article Abstract
Objective: To estimate the annual cost associated with obstetric events in women of reproductive age with immune-mediated inflammatory diseases, from the perspective of the National Healthcare System.
Methods: A cost-analysis was developed to estimate the impact associated with obstetric events in women of reproductive age with psoriasis (PSO), psoriatic arthritis (PsA), rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA). The analysis considered complications during fertility and conception, in pregnancy and in the postpartum. All parameters were validated and agreed by a multidisciplinary expert panel. Unitary costs (€,2019) were obtained from national, local databases.
Results: During fertility and conception, an annual cost per patient of €229 was estimated for a preconception consultation in a patient with PSO, of €3642 for a preconception consultation in patients with PsA, RA and axSpA and €4339 for assisted reproduction. Women with complications in pregnancy had an annual cost per patient of €1214 for a miscarriage in the first trimester, €4419 for a late miscarriage in the second trimester, €11,260 for preeclampsia €3188 for restricted intrauterine growth and €12,131 for threat of premature delivery. In the postpartum, an annual cost per patient of €120,364, €44,709, and €5507 were estimated associated with admissions to neonatology of premature infants of <28, 28-32 and 33-37 weeks, respectively.
Conclusions: This analysis provides insight on the economic burden of complications associated with women of reproductive age for immune-mediated diseases (PSO, PsA, RA, axSpA). Individualization of treatment, additional and close monitoring may reduce the risk and burden of these complications.
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| http://dx.doi.org/10.1016/j.reumae.2021.04.001 | DOI Listing |
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