Dietary l-carnitine supplementation recovers the increased pH and hardness in fillets caused by high-fat diet in Nile tilapia (Oreochromis niloticus).

Food Chem

Laboratory of Aquaculture Nutrition and Environmental Health (LANEH), School of Life Sciences, East China Normal University, Shanghai 200241, PR China; ECNU-UDSM Joint Research Center for Aquaculture and Fish Biology (JRCAFB), Shanghai, PR China. Electronic address:

Published: July 2022

AI Article Synopsis

  • High-fat diets (HFD) negatively impact the quality of fish flesh, leading to increased fat deposition and changes in muscle characteristics.
  • Supplementing HFD with l-carnitine improves lipid metabolism in Nile tilapia, enhancing lactic acid production and muscle fiber size.
  • The study concludes that l-carnitine can mitigate HFD's adverse effects on fish flesh quality by reducing muscle acidity and stress responses.

Article Abstract

The wide use of high-fat diet (HFD) causes negative effects on flesh quality in farmed fish. l-carnitine, a lipid-lowering additive, enhances mitochondrial fatty acid β-oxidation. However its roles in alleviating the effects of HFD on flesh quality in fish are unknown. We fed Nile tilapia with medium-fat diet (MFD, 6% dietary lipid), high-fat diet (HFD, 12% dietary lipid) and HFCD supplemented with l-carnitine (HFCD + 400 mg/kg l-carnitine) for 10 weeks. The HFD-fed fish had higher fat deposition, pH value, myofiber density and flesh hardness than those fed on MFD. However, feeding the fish with the HFCD improved lipid catabolism, which increased significantly lactic acid content and myofiber diameter in muscle, thus reduced pH and hardness values. HFCD also reduced endoplasmic reticulum stress and myofiber apoptosis caused by HFD in the fish. Our study suggests that dietary l-carnitine supplementation alleviates the negative effects of HFD on flesh quality of farmed fish.

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Source
http://dx.doi.org/10.1016/j.foodchem.2022.132367DOI Listing

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