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Higher Levels of Dispositional Mindfulness Are Associated With More Effective Ecological Momentary Intervention Outcomes in Reducing the Frequency of Awake Bruxism Behaviours.
J Oral Rehabil
January 2025
Departamento de Odontologia Restauradora, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil.
Background: Previous research has highlighted the multifactorial nature of awake bruxism (AB), including its associations with stress, anxiety and other psychological factors. Dispositional mindfulness, known for its benefits in enhancing emotional regulation and reducing stress, has not yet been thoroughly investigated in association with AB.
Objective: This study aimed to investigate whether levels of dispositional mindfulness predict the efficacy of ecological momentary intervention (EMI) in reducing the frequency of AB behaviours.
Research on the Composition and Casting Technology of Bronze Arrowheads Unearthed from the Ruins of the Imperial City of the Minyue Kingdom.
Materials (Basel)
January 2025
School of Civil Engineering and Architecture, Wuyi University, No. 358 Baihua Road, Wuyishan 354300, China.
The ruins of the Imperial City of the Minyue Kingdom were an important site of the Minyue Kingdom during the Han Dynasty. Characteristic bronze arrowheads unearthed from the East Gate, with their exquisite craftsmanship, provide important physical evidence for studying ancient bronze casting technology and the military activities of that time. However, there is still a lack of systematic research on the alloy composition, casting process, and chemical stability of these arrowheads in long-term burial environments.
View Article and Find Full Text PDFOptimization of SARS-CoV-2 M Inhibitors by a Structure-Based Multilevel Virtual Screening Method.
Int J Mol Sci
January 2025
Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
With the aim of developing novel anti-SARS-CoV-2 drugs to address the ongoing evolution and emergence of drug-resistant strains, the reported SARS-CoV-2 M inhibitor was selected as a lead to find novel, highly potent, and broad-spectrum inhibitors. Using a fragment-based multilevel virtual screening strategy, 15 hit compounds were identified and subsequently synthesized. Among them, (IC = 1.
View Article and Find Full Text PDFUrinary Proteomic Shifts over Time and Their Associations with eGFR Decline in Chronic Kidney Disease.
Biomolecules
January 2025
Department of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
Chronic kidney disease (CKD) is a progressive condition characterized by declining renal function, with limited biomarkers to predict its progression. The early identification of prognostic biomarkers is crucial for improving patient care and therapeutic strategies. This follow-up study investigated urinary proteomics and clinical outcomes in 18 CKD patients (stages 1-3) and 15 healthy controls using liquid chromatography-mass spectrometry and Mascot-SwissProt for protein identification.
View Article and Find Full Text PDFAdvancing Pediatric Surgery: The Use of HoloLens 2 for 3D Anatomical Reconstructions in Preoperative Planning.
Children (Basel)
December 2024
Pediatric Surgery Department, IRCCS Azienda Ospedaliero, Universitaria di Bologna, Via Massarenti 11, 40138 Bologna, Italy.
Background: In pediatric surgery, a comprehensive knowledge of the child's anatomy is crucial to optimize surgical outcomes and minimize complications. Recent advancements in medical imaging and technology have introduced innovative tools that enhance surgical planning and decision-making.
Methods: This study explores the integration of mixed reality technology, specifically the HoloLens 2 headset, for visualization and interaction with three-dimensional (3D) anatomical reconstructions obtained from computed tomography (CT) scans.
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