AI Article Synopsis
- In vitro studies have enhanced our understanding of how axons navigate and form connections in the nervous system.
- The chapter discusses specific experimental techniques like the rodent "open-book" assay, pre- or postcrossing explant culture, and dissociated neuron culture to explore these mechanisms.
- Findings from these in vitro experiments will be validated or further explored using in vivo genetic methods.
Article Abstract
In vitro studies have provided valuable insights to the function and mechanisms in axon guidance. In this chapter, we will introduce the rodent "open-book" assay, pre- or postcrossing explant culture and the dissociated neuron culture. They have been used to discover mechanism which we have gone on to validate or will confirm using in vivo genetic approaches.
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| http://dx.doi.org/10.1007/978-1-0716-2035-9_18 | DOI Listing |
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