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Pelagic shark intestine as a potential temporary sink for plastic and non-plastic particles.
Mar Environ Res
January 2025
College of Marine Living Resource Sciences and Management, Shanghai Ocean University, Shanghai, China.
Highly migratory pelagic sharks have the potential to serve as carriers of particle contamination in a vast three-dimensional space. We investigate the occurrence, abundance and characteristics of plastic and non-plastic particles in the scroll intestine of the blue shark (Prionace glauca), one of the most abundant pelagic shark species worldwide. We detected both plastic and non-plastic particles in all sections of the intestine, with the posterior region exhibiting the highest concentration.
View Article and Find Full Text PDFHeterologous expression of a recombinant ACE inhibitory peptide LYPVK and its potential antihypertensive action mechanism.
Int J Biol Macromol
January 2025
College of Food Science and Engineering, Ocean University of China, Qingdao 266404, China. Electronic address:
Enzymatic hydrolysis approach is commonly employed for preparation of active peptides, while the limited purity and yield of produced peptides hinder further development of action mechanisms. This study presents the biotechnological approach for the efficient production of recombinant angiotensin converting enzyme (ACE) inhibitory peptide LYPVK and investigates its potential antihypertensive action mechanism. DNA encoding sequence of recombinant peptide was designed to form in tandem, which was expressed in Escherichia coli BL21 (DE3).
View Article and Find Full Text PDFAtrial fibrillation versus. atrial myopathy in thrombogenesis: Two sides of the same coin?
Trends Cardiovasc Med
January 2025
Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark; Medical University of Bialystok, Bialystok, Poland.
Atrial fibrillation (AF) and atrial myopathy are recognized contributors to cardiovascular morbidity, particularly ischemic stroke. AF poses an elevated risk of thrombogenesis due to irregular heart rhythm leading to blood stasis and clot formation. Atrial myopathy, marked by structural and functional alterations in the atria, is emerging as a crucial factor influencing thromboembolic events, independently of AF.
View Article and Find Full Text PDFUnveiling the Dark Side of Flavonoid: Rutin Provokes Hepatotoxicity in Low-Dose 2-Amino-3-methylimidazo [4,5-] Quinoline-Exposed Mice via Regulating Gut Microbiota and Liver Metabolism.
J Agric Food Chem
January 2025
College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, Guangdong 524000, People's Republic of China.
2-Amino-3-methylimidazole [4,5-] quinoline (IQ) is a kind of heterocyclic amine (HCAs) with high carcinogenicity in hot processed meat. Rutin (Ru) is a flavonoid compound with anti-inflammatory and antioxidant properties. However, whether Ru is scatheless under IQ-stimulated potential unhealthy conditions, especially liver function, in vivo, is unknown.
View Article and Find Full Text PDFInovirus-Encoded Peptides Induce Specific Toxicity in .
Viruses
January 2025
Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 511458, China.
is a common opportunistic pathogen associated with nosocomial infections. The primary treatment for infections typically involves antibiotics, which can lead to the emergence of multidrug-resistant strains. Therefore, there is a pressing need for safe and effective alternative methods.
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