Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesis with progressive onset. Laboratory data did not provide any specific information regarding diagnosis, except for positive response to the QuantiFERON Test. Abdominal and pelvic computed tomography (CT) scan showed splenomegaly with multiple nodular, hypodense lesions in the spleen. Spinal cord magnetic resonance imaging (MRI) showed spondyldiscitis at the D10/D11 level with epidural and paravertebral collections responsible for medullary compression. GeneXpert assay on bone biopsy was positive and histological examination objectified granuloma characterized by the presence of central caseous necrosis. The diagnosis of multifocal tuberculosis was retained.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797038 | PMC |
| http://dx.doi.org/10.11604/pamj.2021.40.230.32257 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Proteomic Identification and Clinicopathologic Characterization of Splenic Amyloidosis.
Am J Surg Pathol
January 2023
Departments of Laboratory Medicine and Pathology.
The spleen is a commonly encountered specimen in surgical pathology. However, little is known about the incidence, morphologic pattern, and clinical features of spleens involved by amyloidosis. We retrospectively identified 69 spleen amyloid cases typed using a proteomics-based method between 2008 and 2020.
View Article and Find Full Text PDF[Multinodular splenomegaly revealing multifocal, splenic and spinal tuberculosis: a case report].
Pan Afr Med J
February 2022
Service de Gastroentérologie, Centre Hospitalier Universitaire Mohammed VI Marrakech, Marrakech, Maroc.
Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesis with progressive onset. Laboratory data did not provide any specific information regarding diagnosis, except for positive response to the QuantiFERON Test.
View Article and Find Full Text PDFThrombocytopenia with multiple splenic lesions - histiocytic sarcoma of the spleen without splenomegaly: A case report.
World J Clin Oncol
March 2020
Department of General Surgery, Brandon Regional Hospital, HCA West Florida Division/USF Consortium, Brandon, FL 33511, United States.
Background: Histiocytic sarcoma (HS) of the spleen is reported to be a rare and lethal disease. The clinicopathological features of splenic HS have not been well described. The objective of this paper is to describe the diagnosis and treatment of a case of this rare disease and provide a review of the literature.
View Article and Find Full Text PDFSymptomatic multinodular splenic hamartoma preoperatively suspected as metastatic tumor: a case report.
World J Gastroenterol
August 2014
Rui-Tao Wang, Xin-Sen Xu, Kai Qu, Ji-Gang Bai, Department of Hepatobiliary Surgery, the First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
Splenic hamartoma (SH) is a rare benign tumor usually detected accidentally, which is composed of an aberrant mixture of normal splenic elements. Here, we report a case of 54-year-old man who presented with symptomatic multinodular SH and was admitted initially for thrombocytopenia and anemia. Physical examination revealed that the patients had an anemic appearance and palpable spleen, extending 10 cm below the costal margin.
View Article and Find Full Text PDFDiagnosis and follow-up of Bartonella henselae infection in the spleen of an immunocompetent patient by real-time quantitative PCR.
J Med Microbiol
July 2013
Institute of Microbiology, Department of Health Sciences, 'Magna Graecia' University, Catanzaro, Italy.
Systemic Bartonella henselae infections are unusual in immunocompetent adults. However, here we report one such case of bartonellosis in a 34-year-old patient, who presented with fever and multinodular splenomegaly. We also describe a novel method of identifying Bartonella henselae by real-time quantitative polymerase chain reaction and sequencing of amplified products.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!