Arterial mapping and 99mTc-macroaggregated albumin (99mTc-MAA) hepatic perfusion imaging are routinely performed before 90Y radioembolization of hepatic tumors. These procedures serve multiple purposes, including an anatomical survey of hepatic arterial anatomy, interrogating expected microsphere distribution to avoid nontargeted embolization during therapy, and evaluating for possible hepatopulmonary shunting. We present a case where 99mTc-MAA planar images revealed unexpected soft tissue uptake within the left forearm, an unexpected complication that may result from residual 99mTc-MAA in the catheter being expelled as the catheter is removed, which is particularly important to avoid during the 90Y radioembolization procedure given the risk for associated radionecrosis.
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http://dx.doi.org/10.1097/RLU.0000000000004090 | DOI Listing |
Rev Esp Med Nucl Imagen Mol
December 2022
Unidad de Medicina Nuclear. Hospital Universitario Juan Ramón Jiménez. Ronda Norte, s/n, 21005, Huelva, España.
Aim: To analyze the sample of pregnant patients who underwent pulmonary perfusion scintigraphy to rule out the pulmonary embolism (PE) suspicion during the acute COVID-19 infection hospitalization period in our hospital.
Material And Methods: SPECT scintigraphy with a reduced dose (111 MBq) of 99mTc-macroaggregated albumin was performed in all of the patients (n=5). The obtained images were interpreted by comparing the findings with the radiological images according to the PISAPED criteria.
Med Phys
August 2022
Biomedical Imaging Laboratory (BIG), Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Taipa, Macau SAR, China.
Purpose: We aimed to evaluate respiratory impacts on static and respiratory gated (RG) Tc-MAA SPECT in terms of respiratory motion (RM) blur, attenuation correction (AC), and volume-of-interest (VOI) segmentation on lung shunt faction (LSF) and tumor-to-normal liver ratio (TNR) estimation for liver radioembolization therapy planning.
Methods: The XCAT phantom was used to simulate a population of 300 phantoms, modeling various anatomical variations, tumor characteristics, RM amplitudes, LSFs, and TNRs. One hundred and twenty noisy projections of average activity maps near end-expiration (End-EX) and whole respiratory cycle were simulated analytically, modeling attenuation and geometric collimator-detector-response (GCDR).
Clin Nucl Med
May 2022
From the Department of Radiology.
Pulmonary vasculitis is an uncommon type of vasculitis that may cause pulmonary artery stenosis with ensuing ischemic damage to lung tissue. 99mTc-macroaggregated albumin scintigraphy and iodine lung perfusion mapping are useful imaging modalities for assessment of lung perfusion but are not useful for assessing disease activity. On the other hand, 18F-FDG PET/CT is widely used for assessment of vasculitis activity but cannot provide perfusion information.
View Article and Find Full Text PDFArterial mapping and 99mTc-macroaggregated albumin (99mTc-MAA) hepatic perfusion imaging are routinely performed before 90Y radioembolization of hepatic tumors. These procedures serve multiple purposes, including an anatomical survey of hepatic arterial anatomy, interrogating expected microsphere distribution to avoid nontargeted embolization during therapy, and evaluating for possible hepatopulmonary shunting. We present a case where 99mTc-MAA planar images revealed unexpected soft tissue uptake within the left forearm, an unexpected complication that may result from residual 99mTc-MAA in the catheter being expelled as the catheter is removed, which is particularly important to avoid during the 90Y radioembolization procedure given the risk for associated radionecrosis.
View Article and Find Full Text PDFDiagn Interv Radiol
November 2021
Department of Nuclear Medicine, Saint Luc University Hospital and King Albert II Cancer Institute, Brussels, Belgium.
Purpose: We aimed to determine whether antireflux (ARC) catheter may result in better tumor targeting in liver radioembolization using 90Y-resin microspheres.
Methods: Patients treated with resin microspheres for hepatocellular carcinoma (HCC) and secondary liver malignancies were retrospectively analyzed. All patients underwent a 99mTc-macroaggregated albumin (99mTc-MAA) single photon emission computed tomography (SPECT) following the planning arteriography with a conventional end-hole catheter.
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