AI Article Synopsis
- Dandruff is a widespread issue related to scalp and skin conditions, and scalp seborrheic dermatitis (SD) represents a more severe form with intense itching and inflammation.
- Histamine is a notable biomarker found in scalps affected by dandruff and SD, although the exact mechanism behind its role is still unclear.
- A study in India utilized advanced testing methods to measure histamine levels in non-invasive scalp samples, finding that those with dandruff or mild to moderate SD had significantly elevated histamine levels compared to healthy scalps.
Article Abstract
Dandruff is a common and challenging complaint associated with type of scalp, skin and population. Scalp seborrheic dermatitis (SD) is a more severe manifestation of dandruff associated with very severe itching and inflammation. Histamine is an interesting biomarker released in scalp affected by dandruff and SD even though the mechanism is not well understood yet. A monocentre clinical study was conducted to confirm the relationship between dandruff/SD and scalp histamine level in an Indian population. Highly sensitive liquid chromatography coupled with mass spectrometry was used for histamine quantification in scalp from samples obtained non-invasively. Results showed that scalps with dandruff and mild to moderate SD had higher histamine levels compared with healthy scalps.
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| http://dx.doi.org/10.1111/exd.14539 | DOI Listing |
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