The objective is to address the issue of uncertainty of causality in so-called medical cases, where an adverse outcome of treatment can be related to a combination of factors (medical error, the severe initial condition of the patient, etc.). A trend is observed to the significant increase in the number of favorable court decisions on patients' claims for compensation for moral injury, even if forensic medical experts concluded that there was only an indirect link between defects in medical care and the adverse outcome. This approach by the courts is viewed critically and is due to, firstly, the absence in Russian law of special evidential theories in favor of the patient, allowing in certain cases (when medical records are improperly maintained, a gross error in treatment occurred, etc.) to determine the positive causality; secondly, this approach is related to use of the binary principle (yes/no) in deciding whether a causality exists instead of a proportional approach based on an assessment of probabilities. Given the significant «weight» of the expert opinion in the total body of evidence in a medical dispute, the practice of limiting the expert to answering that no conclusion can be drawn regarding causality without stating the most probable and rational explanation for the adverse medical outcome was criticized.
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http://dx.doi.org/10.17116/sudmed20226501162 | DOI Listing |
Sci Rep
January 2025
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
There is limited data on the risk of second primary malignancies (SPMs) in Asian melanoma survivors. This study aimed to identify the risk of SPMs in Asian melanoma survivors. Standardized incidence ratios (SIRs) were calculated for overall and specific SPMs.
View Article and Find Full Text PDFBurns
January 2025
Dermatology Hospital, Southern Medical University, Guangzhou, China. Electronic address:
Background: Keloid is a benign skin tumor that result from abnormal wound healing and excessive collagen deposition. The pathogenesis is believed to be linked to genetic predisposition and immune imbalance, although the precise mechanisms remain poorly understood. Current therapeutic approaches may not consistently yield satisfactory outcomes and are often accompanied by potential side effects and risks.
View Article and Find Full Text PDFPLoS One
January 2025
School of Life Course and Population Sciences, King's College London, London, United Kingdom.
Introduction: High-Flow Nasal Therapy (HFNT) is an innovative non-invasive form of respiratory support. Compared to standard oxygen therapy (SOT), there is an equipoise regarding the effect of HFNT on patient-centred outcomes among those at high risk of developing postoperative pulmonary complications after undergoing cardiac surgery. The NOTACS trial aims to determine the clinical and cost-effectiveness of HFNT compared to SOT within 90 days of surgery in the United Kingdom, Australia, and New Zealand.
View Article and Find Full Text PDFCochrane Database Syst Rev
January 2025
Department of Pharmacy Practice, University of Connecticut, Storrs, CT 06269, USA.
Background: Guideline-recommended strategies to interrupt chronic anticoagulation with warfarin or direct oral anticoagulants (DOAC) during the perioperative period of cardiac implantable electronic device (CIED) surgery differ worldwide. There is uncertainty concerning the benefits and harms of interrupted and uninterrupted anticoagulation in patients undergoing CIED surgery.
Objectives: To assess the benefits and harms of interrupted anticoagulation (IAC) with either warfarin or DOAC in the perioperative period of CIED surgery versus uninterrupted anticoagulation (UAC), with or without heparin bridging, during an equivalent time frame, for CIED surgery.
Immun Inflamm Dis
January 2025
Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Background: Revealing the clinical manifestations and associations of COVID-19 before and after negative transition remains an area of significant uncertainty. The aim of this study is to investigate the clinical characteristics observed during and after Omicron infection among a specific population, namely healthcare workers (HCWs).
Methods: From November 4, 2022, to January 15, 2023, HCWs in our hospital were enrolled to document clinical symptoms, prevention, and treatment for COVID-19 using a structured questionnaire.
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