AI Article Synopsis
- * The analysis included 13 randomized controlled trials from 2010 to 2020, finding that both dietary and supplemental omega-3s significantly improved periodontal parameters.
- * The results indicate that omega-3 fatty acids could be a beneficial treatment for periodontitis, suggesting positive effects on gum health.
Article Abstract
Aim: To evaluate the intervention effect of omega-3 fatty acids on changes in periodontal parameters.
Materials And Methods: This meta-analysis included studies published in English language between 2010 and 2020, which were extracted from the Cochrane Library, EMBASE, and PubMed databases. The effects of omega-3 fatty acid intervention were investigated using the amount of omega-3 intake, periodontal pocket depth (PPD), clinical attachment loss (CAL), and bleeding on probing (BOP). The random-effects model was generated for data analysis. To obtain robustness of the model, sensitivity analysis was implemented. Subgroup analyses were performed based on the intervention period for each parameter.
Results: All 13 studies included in the meta-analysis were interventional, randomized controlled trials. Two studies implemented omega-3 fatty acid-rich diets, while 11 studies used supplements. Risk of bias was low, and publication bias was not shown. Meta-analysis showed a statistically significant PPD reduction (standardized mean difference [SMD] = -0.81, absolute mean difference [MD] = -0.44 mm), CAL gain (SMD = -0.77, MD = -0.51 mm), and BOP reduction (SMD = -0.65, MD = -9.45%) for the omega-3 fatty acid intervention overall.
Conclusion: This study suggests that supplemental or dietary intake of omega-3 fatty acids for the treatment of periodontitis may have a positive impact on the disease.
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| http://dx.doi.org/10.1111/jcpe.13603 | DOI Listing |
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