Elesesterpenes A-K (-), eleven new lupane-type triterpenoids, triterpenoid glycosides, and nortriterpenoid were isolated from the leaves of . Their structures and relative configurations were completely elucidated by a combination of diverse methods including physical, spectroscopic data. The absolute configuration of elesesterpenes A-B (-) was defined by single-crystal X-ray diffraction. Meanwhile, all the isolates were evaluated for anti-inflammatory activities on lipopolysaccharide-induced nitric oxide production in BV2 microglial cells, and antiproliferative activities against human hepatoma (HepG2), human lung adenocarcinoma (A549), and human glioma cells (LN229) . It was found that some of them exhibited obvious anti-inflammatory activities and potent antiproliferative activities.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819545 | PMC |
http://dx.doi.org/10.3389/fchem.2021.813764 | DOI Listing |
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