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Malignant transformation of a dysembryoplastic neuroepithelial tumor presenting with intraventricular hemorrhage. | LitMetric

Malignant transformation of a dysembryoplastic neuroepithelial tumor presenting with intraventricular hemorrhage.

Radiol Case Rep

Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.

Published: March 2022

AI Article Synopsis

  • * A case is reported of an 18-year-old woman who experienced malignant transformation of a DNT, leading to severe symptoms like headaches and vomiting, and subsequent intraventricular hemorrhage.
  • * After an emergency surgery to remove the tumor, the woman was diagnosed with a malignant DNT but has had no recurrence of the tumor in the 2 years following the operation.

Article Abstract

Dysembryoplastic neuroepithelial tumors (DNTs) are benign brain tumors classified as grade 1 in the 2021 World Health Organization (WHO) classification of central nervous system tumors. DNTs rarely undergo malignant transformation and cause symptomatic intracranial hemorrhage. We report a case of malignant transformation of DNT presenting with intraventricular hemorrhage and review the literature on malignant transformation of DNTs. An 18-year-old woman with a history of epilepsy presented with a sudden headache and vomiting. Radiological examination revealed a mass lesion in the left parietal lobe and intraventricular hemorrhage. The patient underwent an emergency craniotomy for brain tumor resection. The lesion was pathologically diagnosed as a malignant transformation of DNT. She had been followed up without tumor recurrence for 2 years after surgery.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813558PMC
http://dx.doi.org/10.1016/j.radcr.2022.01.014DOI Listing

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