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Hypereosinophilic syndrome presenting as eosinophilic gastroenteritis exacerbated by clopidogrel bisulphate.
Rom J Intern Med
December 2023
Department of Endocrinology, Metabolism and Nephrology Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan.
Clopidogrel is a widely prescribed prodrug with antithrombotic activity that functions by irreversibly inhibiting the P2Y12 receptors on platelets; nevertheless, drug-induced eosinophilia from this drug is rarely reported. An 81-year-old man was diagnosed with cerebral infarction 2 months earlier and was admitted to our hospital with rash, fever, wheezing, and stomach discomfort after being initiated with clopidogrel treatment. Based on his medical history, chest CT, and gastroscopy, we diagnosed him with clopidogrel-induced hypereosinophilic syndrome.
View Article and Find Full Text PDFClopidogrel-induced Eosinophilia and Hypercalcemia with Multiple Organ Lesions Including Eosinophilic Pneumonia.
Intern Med
September 2022
Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Japan.
Clopidogrel-induced Eosinophilia with Hypercalcemia.
Intern Med
September 2022
Department of Respiratory Medicine, Osaka Metropolitan University Graduate School of Medicine, Japan.
There are few cases describing the association of eosinophilia with hypercalcemia, and drug-induced eosinophilia with hypercalcemia has not been reported. A 74-year-old man had been diagnosed with asthma 4 months earlier. He was admitted due to eosinophilia with hypercalcemia.
View Article and Find Full Text PDFSevere clopidogrel-induced DRESS with eosinophilic pneumonia associated with Epstein-Barr virus reactivation.
Respirol Case Rep
April 2020
Clinical Research Center National Hospital Organization, Kinki-Chuo Chest Medical Center Osaka Japan.
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a type of hypersensitivity drug reaction. Here, we report the case of a 78-year-old man who presented with a rash, fever, dry cough, and swollen parotid glands who had been prescribed clopidogrel for one year. Computed tomography showed consolidation and interlobular septal thickening with enlarged mediastinal lymph nodes.
View Article and Find Full Text PDF[A case of clopidogrel-induced eosinophilic pneumonia].
Nihon Kokyuki Gakkai Zasshi
November 2011
Department of Respiratory Medicine, Tokyo Kosei Nenkin Hospital.
An 83-year-old man had been prescribed clopidogrel for pontine infarction since 8 months previously, and had had a cough for the last 2 weeks of this period. Laboratory examinations on admission showed a marked increase in eosinophils and elevated serum immunoglobulin E levels. Chest radiography showed bilateral ground-glass opacities, mild reticulation, and interlobar pleural effusion in the minor fissure.
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