A man aged 26 years presented with complaints of diminution of vision in his right eye for 1 year following a fist injury. He had a history of laser-assisted in situ keratomileusis in both eyes 5 years earlier. On examination, his uncorrected distance visual acuity (UDVA) in the right eye was 1.0 logMAR. Slit-lamp examination of the right eye revealed a superotemporal dislocation of the flap with coexisting epithelial ingrowth encroaching the pupillary area. Due to the presence of long-standing fixed flap folds, a flap amputation was performed along with removal of the epithelial ingrowth using 0.02% mitomycin C as adjunct. Postoperatively, the UDVA was 0.3 logMAR on day 1, which improved to 0.2 logMAR at 1 week. At 1 year, the UDVA was 0.2 logMAR improving to 0.1 logMAR with refraction, with minimal paracentral corneal haze and no signs of corneal ectasia.
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http://dx.doi.org/10.1136/bcr-2021-247068 | DOI Listing |
J Clin Pediatr Dent
November 2024
Department of Conservative Dentistry, College of Dentistry, Dankook University, 31116 Cheonan, Republic of Korea.
This report presents three cases of separated root tip formation following traumatic injury with or without inflammation. The first case showed continued separate apical root formation; however, development of the main root with bony ingrowth was absent. The second case showed that separated root formation continued under the 2-year inflammatory conditions, even after apexification.
View Article and Find Full Text PDFAm J Ophthalmol Case Rep
December 2024
Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Purpose: This study reports a case of Crohn's disease-associated keratopathy that progressed with disease activity.
Observations: A 29-year-old man diagnosed with Crohn's disease and receiving systemic adalimumab therapy, presented with an irregular epithelial surface, superior corneal opacity, subepithelial infiltration, pannus with new vessel ingrowth, and punctate epithelial erosions in both corneas. Changes in ophthalmological findings were checked during regular outpatient follow-ups.
Am J Ophthalmol Case Rep
December 2024
Ophthalmology Department, Xinjiang 474 Hospital, Urumqi, 830011, Xinjiang Autonomous Region, China.
Purpose: To analyze the diagnostic process, treatment, and post-operative outcomes of a unique case involving a late-onset (24 years post) traumatic corneal flap displacement after Laser-assisted in situ keratomileusis (LASIK) surgery due to a plant-related trauma. with an emphasis on the accompanying extensive epithelial ingrowth beneath the flap.
Observations: A 59-year-old male patient experienced corneal flap displacement 24 years post-LASIK due to a minor plant-related trauma.
SAGE Open Med Case Rep
September 2024
Department of Ophthalmology, Xinjiang 474 Hospital (The Former 474 Hospital of the People's Liberation Army), Urumqi, Xinjiang Autonomous Region, China.
Post femtosecond laser-assisted in situ keratomileusis corneal flap inversion trauma is an exceptionally rare and challenging complication in ophthalmology, highlighted by a case involving a 29-year-old woman who suffered an eye injury from ice chips 10 months after undergoing bilateral femtosecond laser-assisted in situ keratomileusis surgery. The injury led to a corneal flap inversion and melting, exacerbated by a delay in seeking treatment due to the pandemic. When she finally presented for medical attention, her vision was severely compromised, with dense epithelial ingrowth obstructing the visual axis or blocking the pupillary entrance.
View Article and Find Full Text PDFACS Appl Mater Interfaces
October 2024
Department of Cariology, Restorative Sciences, and Endodontics, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48104, United States.
Barrier membranes (BM) for guided bone regeneration (GBR) aim to support the osteogenic healing process of a defined bony defect by excluding epithelial (gingival) ingrowth and enabling osteoprogenitor and stem cells to proliferate and differentiate into bone tissue. Currently, the most widely used membranes for these approaches are collagen-derived, and there is a discrepancy in defining the optimal collagen membrane in terms of biocompatibility, strength, and degradation rates. Motivated by these clinical observations, we designed a collagen-free membrane based on l-valine--l-phenylalanine-poly(ester urea) (PEU) copolymer via electrospinning.
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