The purpose of the study is to develop a pregravid preparation algorithm for women suffering from chronic endometritis associated with infertility using therapeutic physical factors. There have been observed 60 patients of reproductive age suffering from chronic endometritis associated with infertility. By simple randomization, two groups were formed: the group of comparison included 30 patients who were treated in accordance with clinical guidelines - antibacterial therapy and simultaneous physiotherapy (magnetic laser therapy, color-stimulation therapy); the main group included 30 patients. They had intrauterine drug instillations additionally to the programme of treatment in stationary conditions, and the patients on an outpatient basis had a complex clay treatment. Performance control was carried out according to the dynamics of immune status indicators, ultrasound and immunohistochemical parameters. After inpatient treatment, the main group showed statistically significant regression of clinical symptoms and normalization of the menstrual cycle in 100% of the cases; and 86.7% of patients showed a significantly significant increase in endometrial thickness, an improvement in estrogen expression in the stroma after the outpatient stage with the use of clay treatment, which generally made it possible to restore reproductive function in 40% of the cases. In the comparison group, the positive dynamics of the studied indicators were significantly lower (p<0.05). There has been developed an algorithm for pregravid preparation of women suffering from chronic endometritis associated with infertility, based on stage-by-stage rehabilitation measures using pharmacotherapy and therapeutic physical factors which ensure the restoration of reproductive function.
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