AI Article Synopsis
- The study focuses on a silica-based monolithic stationary phase modified with trioctyl(3/4-vinylbenzyl)phosphonium chloride, revealing its unique morphology and composition, which includes 38.8% silicon, 60.2% carbon, and 1.0% phosphorus.
- Evaluation of this new stationary phase through liquid chromatography shows its effectiveness in separating a variety of compounds such as alkylbenzenes and aromatic carboxylic acids.
- The ionic liquid-based stationary column outperforms traditional phases like Phenyl-, C8-, and C18 in separation selectivity and demonstrates high efficiency across a wider range of structurally diverse compounds.
Article Abstract
The morphology, composition, and selectivity of a silica-based monolithic stationary phase, grafted by a layer of trioctyl(3/4-vinylbenzyl)phosphonium chloride ([P]Cl), is presented. The results of elemental analysis confirmed that the prepared stationary phase contains 38.8 at.% of silicon, 60.2 at.% of carbon, and 1.0 at.% of phosphorus. Capillary columns (150 × 0.1 mm) for liquid chromatography were evaluated using alkylbenzenes, monosubstituted benzenes, polyaromatic compounds, substituted benzene regioisomers, and aromatic carboxylic and amino acids. The prepared ionic liquid (IL)-based stationary phase exhibits hydrophobic, hydrophilic, and electrostatic interactions, as confirmed by experiments on the evaluation of the effect of the mobile phase composition (content of acetonitrile and ammonium formate) on the isocratic chromatographic separation. Thus, the IL-based capillary column demonstrates a unique separation selectivity compared to Phenyl-, C8-, and C18-stationary phases, and high efficiency for an expanding number of structurally diverse compounds.
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| http://dx.doi.org/10.1016/j.chroma.2022.462866 | DOI Listing |
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