Solitary asymptomatic lobular perianal nodule on an infant.

Dermatol Online J

Department of Dermatology, University of Virginia, Charlottesville, Virginia, USA.

Published: October 2021

Folliculosebaceous cystic hamartoma (FSCH) is a benign lesion that presents as a solitary papule or nodule that typically affects the face and scalp of adults. A few reports have observed a congenital presentation. We present an infant boy exhibiting a tumor with overlap features between an FSCH and fibrofolliculoma in the perianal region that was first noticed at 6 months of age. The histological examination showed a hamartomatous benign proliferation of hair follicles and disordered sebaceous glands, which is consistent with the infundibular structures and radiating sebaceous glands that are typically observed in previously reported cases of FSCH. Sebaceous differentiation is a hallmark feature of FSCH. Folliculosebaceous cystic hamartoma is believed to be a late-stage form of trichofolliculoma (TF). Another consideration is that FSCH and TF are two distinct entities set apart by their degree of sebaceous or follicular differentiation and development of the mesenchymal stroma.

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http://dx.doi.org/10.5070/D3271055628DOI Listing

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Article Synopsis
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  • The standard treatment for FSCH is surgical excision, and post-surgery, the patient has not experienced any recurrence, emphasizing the need to distinguish FSCH from EIC in similar cases.
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Article Synopsis
  • - A 12-year-old girl had a rare benign skin cyst on her scalp, which was found to contain features of both pilar (hair follicle) and apocrine (sweat gland) differentiation.
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Giant Folliculosebaceous Cystic Hamartoma of the Face.

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Folliculosebaceous cystic hamartoma (FSCH) is a rare and benign form of cutaneous hamartomas. These skin lesions often lead to clinical and histopathological misdiagnosis due to their similarities to cutaneous lesions with overproduction of clustered sebaceous glands. Clinically, the lesions often present as solitary, skin-colored, pedunculated warts to cauliflower-like, exophytic papules and nodules, usually with a diameter ranging 0.

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