Thermal strain imaging (TSI) uses echo shifts in ultrasonic B-scan images to estimate changes in temperature which is of great values for thermotherapies. However, for in vivo applications, it is difficult to overcome the artifacts and errors arising from physiological motions. Here, a respiration separated TSI (RS-TSI) method is proposed, which can be considered as carrying out TSI in each of the exhalation and inhalation phases and then combining the results. Normalized cross correlation (NXcorr) coefficient between RF images along the timeline are used to extract the respiratory frequency, after which reference frames are selected to identify the exhalation and inhalation phases, and the two phases are divided quasi-periodically. RF images belonging to both phases are selected by applying NXcorr thresholds, and motion compensation together with a second frame selection helps to obtain two finely matched image sequences. After TSI calculations for each phase, the two processes are merged into one through extrapolation and interphase averaging. Compared to TSI based on dynamic frame selection (DFS), RS-TSI ensures that frames are selected during both the exhalation and inhalation phases while setting the frame selection range according to the respiratory frequency helps to improve motion compensation. The temporal intervals of TSI output are approximately half that employing DFS.
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http://dx.doi.org/10.1109/TUFFC.2022.3149287 | DOI Listing |
Int J Comput Assist Radiol Surg
January 2025
Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA.
Purpose: Pulmonary perfusion imaging is a key lung health indicator with clinical utility as a diagnostic and treatment planning tool. However, current nuclear medicine modalities face challenges like low spatial resolution and long acquisition times which limit clinical utility to non-emergency settings and often placing extra financial burden on the patient. This study introduces a novel deep learning approach to predict perfusion imaging from non-contrast inhale and exhale computed tomography scans (IE-CT).
View Article and Find Full Text PDFWorld Allergy Organ J
January 2025
Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy.
Background: This study aimed to evaluate the impact of severe asthma (SA) treatments after 12 months in achieving clinical remission (CR) within the context of the Severe Asthma Network in Italy (SANI) using the recent SANI definition of CR on treatment.
Methods: CR has been defined by SANI as complete, partial, and no CR. Complete CR is defined by the absence of oral corticosteroids (OCS), no symptoms, no exacerbations, and stable lung function, and partial CR requires the absence of OCS and the fulfillment of 2 out of the other 3 criteria.
Respir Physiol Neurobiol
January 2025
School of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Sydney, NSW 2007, Australia. Electronic address:
Central and Obstructive Sleep Apnea (CSA and OSA), Chronic Obstructive Pulmonary Disease (COPD), and Obesity Hypoventilation Syndrome (OHS) disrupt breathing patterns, posing significant health risks and reducing the quality of life. Bilevel Positive Airway Pressure (BiPAP) therapy offers adjustable inhalation and exhalation pressures, potentially enhancing treatment adaptability for the above diseases. This is the first-ever study that employs Computational Fluid Dynamics (CFD) to examine the biomechanical impacts of BiPAP under four settings: Inspiratory Positive Airway Pressure (IPAP)/Expiratory Positive Airway Pressure (EPAP) of 12/8, 16/6, and 18/8 cmHO, compared to a without-BiPAP scenario of zero-gauge pressure.
View Article and Find Full Text PDFCureus
December 2024
Department of Radiological Technology, Fujieda Municipal General Hospital, Fujieda, JPN.
Purpose This study aimed to clarify which positions are beneficial for patients with pathological lung diseases, such as acute respiratory distress syndrome, by obtaining lung ventilation and deformable vector field (DVF) images using Deformable Image Registration (DIR). Methods Thirteen healthy volunteers (5 female, 8 male) provided informed consent to participate to observe changes in normal lungs. DIR imaging was processed using the B-spline algorithm to obtain BH-CTVI (inhale, exhale) in four body positions (supine, prone, right lateral, left lateral) using DIR-based breath-hold CT ventilation imaging (BH-CTVI).
View Article and Find Full Text PDFSci Rep
January 2025
Department of Mechanical Engineering, PSG Institute of Technology and Applied Research, Coimbatore, 641026, India.
Typical waveforms used for the simulation of pressure and volume-controlled ventilation in medical ventilators have been extensively studied in the literature. The majority of simulation studies reported employ the step pattern or ramp pattern to model the pressure and flow variations in pressure/volume-controlled ventilation. It was observed that the above waveforms tend to add to the discomfort level of patients due to the presence of jerks in derivatives of pressure/flow variations; the pressure/flow variation of air and oxygen mixture should be smooth so that the patient discomfort is kept at a minimal level.
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